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08062

Sigma-Aldrich

Protein G′ from Streptococcus sp.

recombinant, expressed in E. coli

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Synonym(s):
IgG F(c)-Receptor
MDL number:
NACRES:
NA.26

biological source

bacterial (Streptococcus sp.)

Quality Level

recombinant

expressed in E. coli

form

lyophilized solid

mol wt

~30 kDa

capacity

~5 mg/mg, solid binding capacity (IgG)

storage temp.

−20°C

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P8170P329619459
vibrant-m

P3296

Protein G Sepharose, Fast Flow

vibrant-m

19459

Protein G recombinant

form

lyophilized solid

form

lyophilized powder

form

aqueous ethanol suspension

form

-

mol wt

~30 kDa

mol wt

-

mol wt

-

mol wt

Mr ~31800

storage temp.

−20°C

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

−20°C

recombinant

expressed in E. coli

recombinant

expressed in unspecified host

recombinant

expressed in E. coli

recombinant

-

capacity

~5 mg/mg, solid binding capacity (IgG)

capacity

-

capacity

-

capacity

-

General description

Protein G, a cell wall protein, is obtained from group G streptococci. The extracellular part of this protein is made of two/three small domains or serum albumin binding (GA domains) and two/three immunoglobulin (IgG) binding domains (B domains).
Genetically engineered truncated protein G; retains affinity for IgG, but lacks albumin and Fab binding sites and membrane-binding regions.

Application

Protein G′ from Streptococcus sp. has been used in in vitro actin labeling assay.

Biochem/physiol Actions

Protein G can bind all the human and mouse IgG subclasses. It can bind to both the fragment crystallizable (Fc) and antigen-binding fragment (Fab) components of the antibody.

Physical form

lyophilized powder in a Tris-HCl buffer, pH 7.5

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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25G
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