C0685000

Cefotaxime sodium

European Pharmacopoeia (EP) Reference Standard

• Synonym(s): Cefotaxime sodium salt, Cefotaxim sodium salt
• Empirical Formula (Hill Notation): C₁₆H₁₆N₅NaO₇S₂
• CAS Number: 64485-93-4
• Molecular Weight: 477.45
• Beilstein: 5711411
• MDL number: MFCD00079073
• UNSPSC Code: 41116107
• PubChem Substance ID: 329774812
• NACRES: NA.24

Properties

• grade: pharmaceutical primary standard
• API family: cefotaxime
• manufacturer/tradename: EDQM
• application(s): pharmaceutical (small molecule)
• format: neat
• SMILES string: [Na+].[H][C@]12SCC(COC(C)=O)=C(N1C(=O)[C@H]2NC(=O)C(=N/OC)\c3csc(N)n3)C([O-])=O
• InChI: 1S/C16H17N5O7S2.Na/c1-6(22)28-3-7-4-29-14-10(13(24)21(14)11(7)15(25)26)19-12(23)9(20-27-2)8-5-30-16(17)18-8;/h5,10,14H,3-4H2,1-2H3,(H2,17,18)(H,19,23)(H,25,26);/q;+1/p-1/b20-9-;/t10-,14-;/m1./s1
• InChI key: AZZMGZXNTDTSME-JUZDKLSSSA-M

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Cefotaxime sodium EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Biochem/physiol Actions

Cefotaxim inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs) which inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell walls. As a result, bacteria lyse due to cell wall autolytic enzymes.

Mode of Action: Inhibits bacterial cell wall synthesis.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Broad spectrum third generation cephalosporin antibiotic.

Sales restrictions may apply.

Safety Information

• Pictograms: GHS08
• Signal Word: Danger
• Hazard Statements: H317,H334
• Precautionary Statements: P261 - P280 - P284 - P304 + P340 - P333 + P313 - P342 + P311
• Hazard Classifications: Resp. Sens. 1 - Skin Sens. 1
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable