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L4509

Sodium dodecyl sulfate

greener alternative

ReagentPlus®, ≥98.5% (GC)

Sodium dodecyl sulfate

Synonym(s):

Dodecyl sodium sulfate, Dodecyl sulfate sodium salt, Lauryl sulfate sodium salt, SDS, Sodium lauryl sulfate

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10 g
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$43.60
25 g
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$57.20
100 g
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$105.00
250 g
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$227.00
500 g
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$416.00
1 kg
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$739.00

About This Item

Linear Formula:
CH3(CH2)11OSO3Na
CAS Number:
Molecular Weight:
288.38
NACRES:
NA.21
PubChem Substance ID:
eCl@ss:
39093306
UNSPSC Code:
12161900
EC Number:
205-788-1
MDL number:
Beilstein/REAXYS Number:
3599286

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biological source

synthetic

Quality Level

description

anionic

product line

ReagentPlus®

assay

≥98.5% (GC)

form

powder

mol wt

micellar avg mol wt 18,000

greener alternative product characteristics

Catalysis
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

aggregation number

62

impurities

<2.0% water (Karl Fischer)

CMC

7-10 mM (20-25°C)

mp

204-207 °C (lit.)

transition temp

cloud point >100 °C

solubility

water: soluble

density

0.425 g/cm3

cation traces

Na: 7.0-9.0%

HLB

40

application(s)

advanced drug delivery

greener alternative category

SMILES string

[Na+].CCCCCCCCCCCCOS([O-])(=O)=O

InChI

1S/C12H26O4S.Na/c1-2-3-4-5-6-7-8-9-10-11-12-16-17(13,14)15;/h2-12H2,1H3,(H,13,14,15);/q;+1/p-1

InChI key

DBMJMQXJHONAFJ-UHFFFAOYSA-M

General description

Sodium dodecyl sulfate (SDS), or sodium lauryl sulfate, is widely recognized as an anionic surfactant within the organosulfate class of organic compounds. Its effectiveness as a detergent spans both ionic and anionic conditions. SDS plays a critical role as a protein denaturant, facilitating the solubilization and denaturation of proteins in procedures like protein extraction and SDS-PAGE. Its significance in the electrophoretic separation of proteins and lipids establishes its indispensability for the examination of these molecules in diverse biological experiments. In conclusion, Sodium dodecyl sulfate proves to be an indispensable element in the exploration of biological molecules within the realms of biochemical and cell biology research.
We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. This product is used as a surfactant to enhance catalysis.  Click here for more information.

Application

Anionic detergent
Sodium dodecyl sulphate (SDS) has been used:
  • in the characterization of Enterobacteriaceae strain based on sensitivity to selective compounds
  • to treat human skin in vitro and in vivo to evaluate the role of nuclear localization of 27-kDa heat shock protein (HSP27) in potential skin irritation
  • in the decellularization of porcine heart valve tissue
  • to treat sperm for in vitro induction of sperm decondensation

Biochem/physiol Actions

Sodium dodecyl sulphate (SDS) helps to quickly disrupt the biological membranes. It is usually used as one of the major constituent of several reagents, that are used to purify nucleic acids. SDS can block the activity of RNase and deoxyribonuclease (DNase).

Features and Benefits

  • Suitable for Cell Biology and Biochemical Research
  • High purity chemical suitable for multiple research applications

Other Notes

For additional information on our range of Biochemicals, please complete this form.

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

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This Item
4361436286271726
form

powder

form

solid

form

(Rods)

form

rod

assay

≥98.5% (GC)

assay

≥99.0%

assay

≥90% ((Assay))

assay

≥99.0% (GC)

aggregation number

62

aggregation number

-

aggregation number

-

aggregation number

-

cation traces

Na: 7.0-9.0%

cation traces

heavy metals (as Pb): ≤0.002%

cation traces

-

cation traces

-

Quality Level

200

Quality Level

200

Quality Level

100

Quality Level

100

density

0.425 g/cm3

density

1.03 g/cm3 at 20 °C

density

(1.03 g/cm3 at 20 °C (68 °F))

density

-


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Danger

Hazard Classifications

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Flam. Sol. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

4.1B - Flammable solid hazardous materials

flash_point_f

338.0 °F

flash_point_c

170 °C

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges



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Sub-Micellar Concentration of Sodium Dodecyl Sulphate Prevents Thermal Denaturation Induced Aggregation of Plant Lectin, Jacalin
Lavanya V, et al
The Protein Journal, 36(1), 17-27 (2017)
A rapid and reliable alternative to ISO 21528-1: 2004 for detection of Enterobacteriaceae
Joosten H, et al.
International Journal of Food Microbiology, 125(3), 344-346 (2008)
Utility of light scatter in the morphological analysis of sperm
Zucker RM, et al.
Cytometry, 39-47 (1992)



Global Trade Item Number

SKUGTIN
L4509-100G04061835546060
L4509-25G04061833957561
L4509-1KG04061835546084
L4509-500G04061835546107
L4509-250G04061835546091
L4509-10G04061835546077

Questions

1–3 of 3 Questions  
  1. I want to verify if SDs is clean in instrument, does TOC analysis allow to determine if residu still in solution

    1 answer
    1. Carbon analysis provides an idea as to the percentage of carbon that exists in sodium dodecyl sulfate. Residue testing can be performed after solution preparation and filtration. The mass of retentate after a solution is filtered would allow the determination of the amount of insoluble material present. Unfortunately, this test is not performed on this product as this product is not a solution.

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  3. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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