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L5750

Sigma-Aldrich

Sodium dodecyl sulfate

92.5-100.5% based on total alkyl sulfate content basis

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Synonym(s):
Dodecyl sodium sulfate, Dodecyl sulfate sodium salt, Lauryl sulfate sodium salt, SDS, Sodium lauryl sulfate
Linear Formula:
CH3(CH2)11OSO3Na
CAS Number:
Molecular Weight:
288.38
Beilstein:
3599286
EC Number:
MDL number:
eCl@ss:
39093306
PubChem Substance ID:
NACRES:
NA.21

description

anionic

Quality Level

Assay

92.5-100.5% based on total alkyl sulfate content basis

mol wt

288.38 g/mol

aggregation number

62

CMC

7-10 mM (20-25°C)

mp

204-207 °C (lit.)

transition temp

cloud point >100 °C

solubility

water: soluble

HLB

40

SMILES string

[Na+].CCCCCCCCCCCCOS([O-])(=O)=O

InChI

1S/C12H26O4S.Na/c1-2-3-4-5-6-7-8-9-10-11-12-16-17(13,14)15;/h2-12H2,1H3,(H,13,14,15);/q;+1/p-1

InChI key

DBMJMQXJHONAFJ-UHFFFAOYSA-M

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This Item
L45097172975746
Sodium dodecyl sulfate 92.5-100.5% based on total alkyl sulfate content basis

Sigma-Aldrich

L5750

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Sodium dodecyl sulfate ReagentPlus®, ≥98.5% (GC)

Sigma-Aldrich

L4509

Sodium dodecyl sulfate

Sodium dodecyl sulfate ≥98.0% (GC)

Sigma-Aldrich

71729

Sodium dodecyl sulfate

Sodium dodecyl sulfate ≥99.0% (GC), dust-free pellets

Sigma-Aldrich

75746

Sodium dodecyl sulfate

assay

92.5-100.5% based on total alkyl sulfate content basis

assay

≥98.5% (GC)

assay

≥98.0% (GC)

assay

≥99.0% (GC)

mol wt

288.38 g/mol

mol wt

micellar avg mol wt 18,000

mol wt

micellar avg mol wt 18,000

mol wt

average mol wt 18,000

aggregation number

62

aggregation number

62

aggregation number

62

aggregation number

62

CMC

7-10 mM (20-25°C)

CMC

7-10 mM (20-25°C)

CMC

7-10 mM (20-25°C)

CMC

7-10 (lit.)

mp

204-207 °C (lit.)

mp

204-207 °C (lit.)

mp

204-207 °C (lit.)

mp

204-207 °C (lit.)

Application

Sodium dodecyl sulfate has been used:
  • to dissolve insoluble purple formazan in 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) assay
  • to perform SDS–PAGE of yeast tubulin
  • as an additive in linolenic acid solution to assess the total antioxidative activity (TAA) of the bacteria using the linolenic acid test (LA-test)

Anionic detergent

Biochem/physiol Actions

Sodium dodecyl sulfate (SDS)/lauryl sulfate, an ionic detergent has the ability to distract biological membranes. It can block RNase and deoxyribonuclease (DNase) activity. SDS is one of the main constituents of several reagents, that are used to purify nucleic acids. It is also considered as a permeability enhancer in oral formulations.

Quality

Predominantly (approx. 70%) C12; lauryl sulfate, sodium salt; balance consists of higher homologs.

Analysis Note

Actual composition given on label

Pictograms

CorrosionExclamation mark

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Skin Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

338.0 °F

Flash Point(C)

170 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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25G
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MMYOMAG-74K-13

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The two alpha-tubulin isotypes in budding yeast have opposing effects on microtubule dynamics in vitro
Bode CJ, et al.
EMBO Reports, 4(1), 94-99 (2003)
Resilient Ribonucleases
RNA Methodologies (2010)
Two antioxidative lactobacilli strains as promising probiotics
Kullisaar T, et al.
International Journal of Food Microbiology, 72(3), 215-224 (2002)
Safety and efficacy of self-assembling bubble carriers stabilized with sodium dodecyl sulfate for oral delivery of therapeutic proteins
Lin P Y, et al.
Journal of Controlled Release : Official Journal of the Controlled Release Society, 259, 168-175 (2017)
Ursolic, oleanolic and betulinic acids: antibacterial spectra and selectivity indexes.
Fontanay S, et al.
Journal of Ethnopharmacology, 120(2), 272-276 (2008)

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