All Photos(3)

16201

Sigma-Aldrich

Tannic acid

puriss., meets analytical specification of USP, powder

Synonym(s):
Tannin, Gallotannin
Empirical Formula (Hill Notation):
C76H52O46
CAS Number:
Molecular Weight:
1701.20
Beilstein:
8186396
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.21

Quality Level

grade

puriss.

form

powder

autoignition temp.

980 °F

quality

meets analytical specification of USP

impurities

dextrines, gum matters, in accordance
resinous matters, in accordance
≤0.003% heavy metals (as Pb)

ign. residue

≤0.1% (as SO4)

loss

≤9% loss on drying, 105 °C, 2 h

mp

218 °C (lit.)

solubility

H2O: soluble 1 gm in 0.35ml
glycerol: soluble 1gm in 1 ml (warm)
acetone: very soluble
alcohol: freely soluble (Diluted)
alcohol: slightly soluble (Dehydrated)
alcohol: very soluble
benzene: insoluble
carbon disulfide: insoluble
carbon tetrachloride: insoluble
chloroform: insoluble
diethyl ether: insoluble
hexane: insoluble
petroleum ether: insoluble

cation traces

As: ≤3 mg/kg

SMILES string

Oc1cc(cc(O)c1O)C(=O)Oc2cc(cc(O)c2O)C(=O)OC[C@H]3O[C@@H](OC(=O)c4cc(O)c(O)c(OC(=O)c5cc(O)c(O)c(O)c5)c4)[C@H](OC(=O)c6cc(O)c(O)c(OC(=O)c7cc(O)c(O)c(O)c7)c6)[C@@H](OC(=O)c8cc(O)c(O)c(OC(=O)c9cc(O)c(O)c(O)c9)c8)[C@@H]3OC(=O)c%10cc(O)c(O)c(OC(=O)c%11cc(O)c(O)c(O)c%11)c%10

InChI

1S/C76H52O46/c77-32-1-22(2-33(78)53(32)92)67(103)113-47-16-27(11-42(87)58(47)97)66(102)112-21-52-63(119-72(108)28-12-43(88)59(98)48(17-28)114-68(104)23-3-34(79)54(93)35(80)4-23)64(120-73(109)29-13-44(89)60(99)49(18-29)115-69(105)24-5-36(81)55(94)37(82)6-24)65(121-74(110)30-14-45(90)61(100)50(19-30)116-70(106)25-7-38(83)56(95)39(84)8-25)76(118-52)122-75(111)31-15-46(91)62(101)51(20-31)117-71(107)26-9-40(85)57(96)41(86)10-26/h1-20,52,63-65,76-101H,21H2/t52-,63-,64+,65-,76+/m1/s1

InChI key

LRBQNJMCXXYXIU-PPKXGCFTSA-N

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Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

390.2 °F

Flash Point(C)

199 °C

Certificate of Analysis

Certificate of Origin

W A Anderson et al.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 23(4), 295-302 (1975-04-01)
Endogenous mannary gland peroxidase in acinar cells of prelactating and lactating rats is revealed in tannic acid-formaldehyde-glutaraldehyde-fixed tissue by means of the standard diaminobenzidine procedure. Diaminobenzidine cytochemical reaction product is present in perinuclear cisternae, in the granular endoplasmic reticulum and
Yanyan Sun et al.
Anti-cancer drugs, 23(9), 979-990 (2012-07-13)
Tannic acid (TA) has been associated with anticancer functions in multiple tumor types both in vitro and in vivo. However, its effect on ovarian carcinoma cells has not been investigated, and its underlying anticancer mechanism(s) remain unclear. In this study
R C Srivastava et al.
Cancer letters, 153(1-2), 1-5 (2000-04-26)
The deleterious effects of excessive release of nitric oxide (NO) have been implicated in the tissue damage and inflammation. In this study, the effect of various flavonoids and other oxidant scavenging chemical agents have been studied for their ability to
M Chiesi et al.
Biochemical pharmacology, 49(4), 495-501 (1995-02-14)
The effect of natural polyphenols on three isoforms of NO-synthase was investigated. Among the compounds tested, tannin was the most potent, inhibiting endothelial constitutive NO synthase (eNOS) with an IC50 of 2.2 microM. Other NOS isoforms (i.e. neuronal constitutive NOS
Claudia Scattino et al.
Food chemistry, 163, 51-60 (2014-06-11)
In the present study the possibility of enhancing phenolic compound contents in peaches and nectarines by post-harvest irradiation with UV-B was assessed. Fruits of 'Suncrest' and 'Babygold 7' peach and 'Big Top' nectarine cultivars were irradiated with UV-B for 12

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