24366C

SAFC

EX-CELL® Advanced CHO Fed-batch Medium

powder

NACRES:
NA.71

Quality Level

description

Animal-component free
Chemically defined

form

powder

application(s)

cell culture | mammalian: suitable (suspension)

impurities

endotoxin, tested

shipped in

ambient

storage temp.

2-8°C

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General description

EX-CELL® AdvancedCHO Fed-batch Medium is chemically-defined and contains no animal derived components. This newest platform from SAFC has been specifically developed to support growth and productivity across a diverse set of Chinese Hamster Ovary (CHO) cells in fed-batch cultures while still allowing for flexibility in the adjustment of protein quality attributes. This contemporary fed-batch platform was developed using a strategy of Multivariate Analysis to establish correlations in which the formulation components influence critical process and product attributes such as titer, fold expansion, receptor expression, and glycosylation. This platform contains no hypoxanthine and thymidine, L-glutamine, phenol red or 2-mercaptoethanol (2-ME).

This medium is intended to be a part of a fed-batch platform, and used with EX-CELL® Advanced CHO Feed 1 (24367C - with glucose or 24368C - without glucose).

Packaging

100 L in poly drum
24366C-1L
24366C-10L

Linkage

Submit the EX-CELL Advanced CHO Fed-batch request form to get in touch with a SAFC representative.

Legal Information

EX-CELL is a registered trademark of Sigma-Aldrich Co. LLC

pictograms

Exclamation mark

signalword

Warning

hcodes

hazcat

Eye Irrit. 2

storage_class_code

11 - Combustible Solids

WGK Germany

WGK 2

Certificate of Analysis

Certificate of Origin

Articles
In this study, nine commercially available, chemically defined media and feed combinations from different vendors were assessed for producing monoclonal antibody in Chinese hamster ovary (CHO) cells.
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This application note describes the benefits and performance of Cellvento<sup>®</sup> 4CHO-X Expansion Medium designed for multiple cell expansion steps from vial thaw to N-1 stages to generate higher biomass for inoculating fed-batch production bioreactors
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