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85580

SAFC

Spermidine trihydrochloride

From microbial,synthetic, ≥99.0% (AT), nNos inhibitor, powder

Synonym(s):

N-(3-Aminopropyl)-1,4-butanediamine trihydrochloride

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$166.00
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$667.00

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About This Item

Linear Formula:
NH2(CH2)3NH(CH2)4NH2 · 3HCl
CAS Number:
334-50-9
Molecular Weight:
254.63
Beilstein:
3552356
EC Number:
206-379-0
MDL number:
MFCD00012918
UNSPSC Code:
12352204
PubChem Substance ID:
329769390
NACRES:
NA.77

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Product Name

Spermidine trihydrochloride, ≥99.0% (AT)

biological source

microbial
synthetic

Quality Level

200

Assay

≥99.0% (AT)

form

powder

mp

~250 °C (dec.)
257-259 °C (lit.)

solubility

H2O: 0.1 g/mL, clear, colorless

storage temp.

room temp

SMILES string

Cl[H].Cl[H].Cl[H].NCCCCNCCCN

InChI

1S/C7H19N3.3ClH/c8-4-1-2-6-10-7-3-5-9;;;/h10H,1-9H2;3*1H

InChI key

LCNBIHVSOPXFMR-UHFFFAOYSA-N

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This Item
85578S250156766-M
Spermidine trihydrochloride ≥99.0% (AT)

SAFC

85580

Spermidine trihydrochloride

Spermidine trihydrochloride BioXtra, ≥99.5% (AT)

Sigma-Aldrich

85578

Spermidine trihydrochloride

Spermidine trihydrochloride ≥98% (TLC)

Sigma-Aldrich

S2501

Spermidine trihydrochloride

Spermidine, Trihydrochloride Polyamine that plays an important role in the regulation of cellular proliferation and differentiation.

Sigma-Aldrich

56766-M

Spermidine, Trihydrochloride

assay

≥99.0% (AT)

assay

≥99.0% (TLC), ≥99.5% (AT)

assay

≥98% (TLC)

assay

≥98% (TLC)

biological source

microbial, synthetic

biological source

-

biological source

microbial, synthetic

biological source

-

Quality Level

200

Quality Level

100

Quality Level

200

Quality Level

100

form

powder

form

powder

form

powder

form

solid

storage temp.

room temp

storage temp.

-

storage temp.

room temp

storage temp.

10-30°C

solubility

H2O: 0.1 g/mL, clear, colorless

solubility

H2O: 1 M at 20 °C, clear, colorless

solubility

water: 100 mg/mL, clear, colorless

solubility

ethanol: soluble, water: soluble

General description

Spermidine is a polyamine[1] and a trivalent organic cation.[2]

Application

Spermidine trihydrochloride has been used as standard for the detection of biogenic amines using HPLC.[3]

Biochem/physiol Actions

Inhibits neuronal nitric oxide synthase (nNOS). Binds and precipitates DNA; Stimulates T4 polynucleotide kinase activity.
Inhibits neuronal nitric oxide synthase (nNOS). Binds and precipitates DNA; may be used for purification of DNA binding proteins. Stimulates T4 polynucleotide kinase activity.
Spermidine modulates various cellular activities like cellular development and differentiation, stability of DNA and apoptosis.[1]

Disclaimer

Solutions should be sterile-filtered, not autoclaved, if sterile solution is necessary. Spermidine deaminates with time; solutions should be stored frozen. Prepare new solutions frequently.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCN3812
BCCM5076
BCCL3381
BCCK5992
BCCJ1650

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Quality Changes and Shelf-Life of Cultured and Wild Hot-Smoked Mediterranean Horse Mackerel (Trachurus mediterraneus, Steindachner, 1868) at Frozen Storage (-20 pm2 C)
Koral S, et al.
Turkish Journal of Fisheries and Aquatic Sciences, 15(3), 495-504 (2015)
Induction of Autophagy and Apoptosis in Melanoma Treated With Palladacycle Complexes
Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging, 231-247 (2016)
Maegan J Watson et al.
Current protocols, 2(1), e344-e344 (2022-01-19)
The control of mRNA stability is fundamental to gene regulation, and a deeper understanding of this post-transcriptional regulatory step can provide key insights into gene function. Measuring mRNA half-lives directly, however, is challenging. The most common strategies for evaluating mRNA
Restriction Endonucleases and Modification Methylases
Enzymology Primer for Recombinant DNA Technology, 233-306 (1996)
Oliver Hendy et al.
Molecular cell, 82(19), 3598-3612 (2022-09-17)
Gene transcription is a highly regulated process in all animals. In Drosophila, two major transcriptional programs, housekeeping and developmental, have promoters with distinct regulatory compatibilities and nucleosome organization. However, it remains unclear how the differences in chromatin structure relate to
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