Lisa Levine et al.
Scientific reports, 10(1), 6398-6398 (2020-04-15)
Preeclampsia is the most common placental pathology in pregnant females, with increased morbidity and mortality incurred on the mother and the fetus. There is a need for improved biomarkers for diagnosis and monitoring of this condition. Placental syncytiotrophoblasts at the...
Cindy C Shu et al.
Arthritis & rheumatology (Hoboken, N.J.), 68(4), 868-879 (2015-12-05)
To investigate the role of the heparan sulfate (HS) proteoglycan perlecan (HSPG-2) in regulating fibroblast growth factor (FGF) activity, bone and joint growth, and the onset and progression of posttraumatic osteoarthritis (OA) in a mouse gene-knockout model. Maturational changes were...
Chen Dai et al.
Cancer research, 80(19), 4071-4086 (2020-07-08)
The complex yet interrelated connections between cancer metabolism, gene expression, and oncogenic driver genes have the potential to identify novel biomarkers and drug targets with prognostic and therapeutic value. Here we effectively integrated metabolomics and gene expression data from breast...
Multi-Tissue Acceleration of the Mitochondrial Phosphoenolpyruvate Cycle Improves Whole-Body Metabolic Health.
Abulizi, et al.
Cell Metabolism, 32, 751-766 (2021)
Ayako Sasaki et al.
Human cell, 29(1), 37-45 (2015-11-11)
Of two stereoisomers of glucose, only D- and not L-glucose is abundantly found in nature, being utilized as an essential fuel by most organisms. The uptake of D-glucose into mammalian cells occurs through glucose transporters such as GLUTs, and this...