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MilliporeSigma

F1051

Fetal Bovine Serum

Canada origin, sterile-filtered, suitable for cell culture

Fetal Bovine Serum

Synonym(s):

Fetal Calf Sera, Fetal Calf Serum, FBS, FCS, sera, serum

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100 ML

$204.00

500 ML

$785.00

6 X 500 ML

$4,140.00

$204.00


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About This Item

MDL number:
UNSPSC Code:
12352207
NACRES:
NA.71
Biological source:
bovine fetus
Origin:
Canada origin
Sterility:
sterile-filtered
Shipped in:
dry ice

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biological source

bovine fetus

sterility

sterile-filtered

product line

FBS Classic

composition

Bovine IgG, ≤1 mg/mL
Hemoglobin, ≤25 mg/dL

origin

Canada origin

technique(s)

cell culture | mammalian: suitable

impurities

≤10 EU/mL endotoxin

shipped in

dry ice

storage temp.

−20°C

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This Item
F4135F2442F7942
technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | hybridoma: suitable, cell culture | insect: suitable, cell culture | mammalian: suitable

technique(s)

cell culture | hybridoma: suitable, cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

sterility

sterile-filtered

sterility

sterile-filtered

sterility

sterile-filtered

sterility

γ-irradiated, sterile-filtered

origin

Canada origin

origin

USA origin

origin

USA origin

origin

Canada origin

biological source

bovine fetus

biological source

bovine fetus

biological source

bovine fetus

biological source

bovine fetus

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

composition

Bovine IgG, ≤1 mg/mL , Hemoglobin, ≤25 mg/dL

composition

Bovine IgG, ≤1 mg/mL , Hemoglobin, ≤20 mg/dL

composition

Bovine IgG, ≤1 mg/mL , Hemoglobin, ≤20 mg/dL

composition

Bovine IgG, ≤1.0 mg/mL , Hemoglobin, ≤20 mg/dL

General description

FBS blocks reactive oxygen species generation, which otherwise is not eliminated in serum-free media (SFM) systems.[1] It also protects cells from oxidative damage and apoptosis.[2]
Fetal bovine serum is the main component present in almost all media used for the culture of animal cells. It provides serum additives to the cell culture medium, which is essential for supporting growth of a variety of cell types. It is rich in growth factors and protein but low in γ-globulin content.[3][4]

Application

FBS sourced from Canada is used in a broad range of cell culture applications. FBS provides many non-defined growth promoting and survival enhancing factors to cells in culture. It was used as a supplement for different cell cultures.[5][6][7]

Analysis Note

  • Endotoxin and hemoglobin tested
  • Tested for the presence of bacteria, virus, and mycoplasma
  • Triple filtered with 0.1 micron membrane under aseptic conditions

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Irza Sukmana et al.
Journal of biomedical materials research. Part A, 92(4), 1587-1597 (2009-05-14)
We describe an in vitro culture process that uses 100-microm diameter poly(ethylene terephthalate) monofilaments as contact guidance of human umbilical vein endothelial cells (HUVECs) to orient the development of microvessels in a 3D environment. Untreated fibers, distanced either by 0.05
Thomas Sanderson et al.
European journal of pharmacology, 593(1-3), 92-98 (2008-07-22)
Certain lactone-containing secondary plant metabolites display potent biological effects, including anti-tumor activities. This is of particular interest as these compounds appear effective against hormone-dependent cancers, such as those of breast and prostate, of which the incidence is on the rise.
Megha S Even et al.
Trends in biotechnology, 24(3), 105-108 (2006-01-24)
Despite considerable progress in the development of cell culture techniques, including the development of the serum- and protein-free media that now routinely support hybridoma and mammalian cell growth, fetal bovine serum (FBS) supplemented media are still commonly used: a practice
Irza Sukmana et al.
Biomaterials, 31(19), 5091-5099 (2010-03-30)
In the present study, polymer monofilaments were embedded in fibrin seeded with human umbilical vein endothelial cells (HUVEC) to guide HUVEC attachment and migration in order to form oriented vessel-like structures between adjacent monofilaments. Histology and fluorescent fibrin experiments confirmed
Shannon E Clarke et al.
Transgenic research, 23(3), 489-501 (2014-03-14)
Fat-1 transgenic mice, which endogenously convert n-6 PUFA to n-3 PUFA, are a useful tool in health research; however with this model timing of n-3 PUFA enrichment cannot be directly controlled. To add such capability, the novel Cre-recombinase inducible fat-1

Articles

Calcium is an ionically stable divalent cation with important beneficial and toxic properties in cell culture. It is a component of a wide range of cell culture media.

Find answers to frequently asked questions (FAQs) about FBS and other serum products, and links to related products.

Review the basics of using fetal bovine (or calf) serum for cell culture and how sourcing and regulations affect the price of sera for cell-based assays.

Révisez les bases de l'utilisation du sérum bovin (ou de veau) fœtal dans la culture de cellules, et redécouvrez comment la provenance et la réglementation affectent le prix des sérums impliqués dans les tests cellulaires.

Protocols

Protect your investment with best practices for storing and thawing FBS and other sera. Sample FBS for validation in your cell culture protocol.

Related Content

Découvrez notre gamme de sérums de veau fœtal (FBS) et identifiez le FBS adapté à vos besoins et à votre budget. Demander un échantillon de sérum.

Learn how to effectively filter fetal bovine serum (FBS) using Stericup® Quick Release vacuum filtration devices, including flow test data and analysis.

Questions

  1. Do this FBS need heat inactivation?

    1 answer
    1. This product is not heat inactivated. Please see the link below to review heat inactivated Fetal Bovine Serum product options:
      https://www.sigmaaldrich.com/search/heat-inactivated-fetal-bovine-serum?focus=products&page=1&perpage=30&sort=relevance&term=heat-inactivated%20Fetal%20Bovine%20Serum&type=product

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