All Photos(5)

H8125

Sigma-Aldrich

L-Histidine monohydrochloride monohydrate

≥98% (HPLC)

Synonym(s):
L-α-Amino-β-(4-imidazolyl)propionic acid monohydrochloride
Empirical Formula (Hill Notation):
C6H9N3O2 · HCl · H2O
CAS Number:
Molecular Weight:
209.63
Beilstein:
4168261
MDL number:
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.32

Quality Level

assay

≥98% (HPLC)

mp

254 °C (dec.) (lit.)

solubility

H2O: 50 mg/mL, clear, colorless to very faintly yellow

SMILES string

O.Cl.N[C@@H](Cc1c[nH]cn1)C(O)=O

InChI

1S/C6H9N3O2.ClH.H2O/c7-5(6(10)11)1-4-2-8-3-9-4;;/h2-3,5H,1,7H2,(H,8,9)(H,10,11);1H;1H2/t5-;;/m0../s1

InChI key

CMXXUDSWGMGYLZ-XRIGFGBMSA-N

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Application

L-Histidine monohydrochloride monohydrate has been used as a component of broth to match the tuna meat amino acid composition. It has also been used for partial rescue of the IMPL2 (myo-inositol monophosphatase) phenotype during seed development of Arabidopsis.

Packaging

5, 25, 100 g in poly bottle
1 kg in poly bottle
5 kg in poly drum

Biochem/physiol Actions

Histidine takes part in protein methylation. It is associated with the hemoglobin structure and function. Histidine is present in antioxidative dipeptides. It is involved in one-carbon unit metabolism.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Certificate of Analysis

Certificate of Origin

Modelling the effect of temperature, carbon dioxide, water activity and pH on growth and histamine formation by Morganella psychrotolerans
Emborg J and Dalgaard P
International Journal of Food Microbiology, 128(2), 226-233 (2008)
Expression and functions of myo-inositol monophosphatase family genes in seed development of Arabidopsis
Sato Y, et al.
Journal of Plant Research, 124(3), 385-394 (2011)
Yuko Sato et al.
Journal of plant research, 124(3), 385-394 (2010-10-21)
Myo-inositol monophosphatase (IMP) catalyzes the dephosphorylation of myo-inositol 3-phosphate in the last step of myo-inositol biosynthesis. IMP is also important in phosphate metabolism and is required for the biosynthesis of cell wall polysaccharides, phytic acid, and phosphatidylinositol. In Arabidopsis, IMP
Garrett RH and Grisham CM
Biochemistry (2012)
Kiana Khadem-Abbassi et al.
Nanomaterials (Basel, Switzerland), 9(5) (2019-05-07)
This work describes the preparation of molecularly imprinted polymer (MIP)-modified core/shell CdTe0.5S0.5/ZnS quantum dots (QDs). The QDs@MIP particles were used for the selective and sensitive detection of dopamine (DA). Acrylamide, which is able to form hydrogen bonds with DA, and

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