MilliporeSigma
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I9385

Sigma-Aldrich

Anti-Human IgM (μ-chain specific) antibody produced in rabbit

whole antiserum

MDL number:
NACRES:
NA.46

biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

whole antiserum

antibody product type

secondary antibodies

clone

polyclonal

contains

15 mM sodium azide

technique(s)

indirect ELISA: 1:20,000

shipped in

dry ice

storage temp.

−20°C

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I0140I1136I1636
biological source

rabbit

biological source

rabbit

biological source

goat

biological source

goat

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

antibody form

whole antiserum

antibody form

IgG fraction of antiserum

antibody form

whole antiserum

antibody form

whole antiserum

clone

polyclonal

clone

polyclonal

clone

polyclonal

clone

polyclonal

technique(s)

indirect ELISA: 1:20,000

technique(s)

indirect ELISA: 1:100,000

technique(s)

indirect ELISA: 1:40,000, quantitative precipitin assay: 4.0 mg/mL

technique(s)

indirect ELISA: 1:100,000

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

General description

IgM is a pentameric immunoglobulin, with each monomer having a light and heavy chain. The two types of IgM comprise natural and adaptive.

Application

Anti-Human IgM (μ-chain specific) antibody produced in rabbit has been used in enzyme linked immunosorbent assay.

Biochem/physiol Actions

IgM antibodies are present as pentamers in the serum and are produced in response to antigens.
IgM serves as prime antibody in providing defense. It activates complement C1q. It is regarded as a marker for identifying tumor-associated antigens. Hyper-IgM syndrome is implicated with high IgM levels accompanied by low IgA, IgG and IgE levels.

Preparation Note

treated to remove lipoproteins

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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