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Lysozyme human

recombinant, expressed in rice, ≥100,000 units/mg protein, lyophilized powder

Lysobac r Lysozyme, Mucopeptide N-acetylmuramoylhydrolase, Muramidase
CAS Number:
Enzyme Commission number:
MDL number:


expressed in rice

Quality Level


≥90% (SDS-PAGE)


lyophilized powder

specific activity

≥100,000 units/mg protein

mol wt

16.5 kDa

UniProt accession no.

shipped in

dry ice

storage temp.


Gene Information

human ... LYZ(4069)

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General description

Lysozyme is present in tears, saliva and human milk. The human lysozyme expressed in rice grains is an excellent supplemental source of this antimicrobial protein.[1] Lysozyme is mapped to human chromosome 12q15 and corresponds to a molecular weight of 16.5kDa.[2] It is a positively charged and a C-type lysozyme[3] with α and β structural domains.[4]


Lysozyme human has been used:
  • in the interaction studies with polyphenon-60 by calorimetric and spectroscopic techniques[5]
  • in the drug release assay of dexamethasone (DEX) - carbon nanotube based delivery system[6]
  • in the surface plasmon resonance (SPR) for measuring its interaction with human angiotensin I-converting enzyme (ACE)[7]


1, 10 g in glass bottle
Package size based on protein content

Biochem/physiol Actions

Lysozyme is an antibacterial enzyme, which acts on the peptidoglycan layer at the on the N-acetylgluosamine (NAG) and N-acetylmuramic acid linkage, resulting in the lysis of microbial cells.[1] It is a potential anti-inflammatory factor and also has anti-fungal and anti-viral functionality.[3] In inflammatory bowel disease, lysozyme is highly expressed in colonic tissue.[2] Point mutations in lysozyme is implicated in the pathogenesis of hereditary non-neuropathic renal amyloidosis.[4]

Features and Benefits

Lysobac is a breakthrough for bacterial cell lysis and can be used in diagnostic applications, bioprocessing and life science research. It is recombinant human lysozyme produced in an animal-free production system. Animal-free production eliminates the safety risk and inconsistent lot-to-lot performance of hen egg white lysozyme. Lysobac has significantly higher bioactivity than hen egg white lysozyme. One gram replaces 4 grams of hen egg white lysozyme. It also delivers gentle cell lysis, unlike mechanical lysis which can cause protein shear and reduce protein yields by up to 20%.
  • Improves Bacterial Fermentation Efficiency
  • Greater bacterial lysis activity per mg.
  • 1 gram of delivers more lysis activity than 4 grams of HEWL
  • Animal-free and consistent leading to improved regulatory efficiency for drug manufacturing
  • Improved recombinant protein yield compared to mechanical lysis
  • Reduces cost of goods

Unit Definition

One unit will produce a ΔA450 of 0.001 per min at pH 6.24 at 25 °C, using a suspension of Micrococcus lysodeikticus as substrate, in a 2.6 mL reaction mixture (1 cm light path).

Legal Information

Lysobac is a trademark of InVitria

Storage Class Code

11 - Combustible Solids



Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

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Certificate of Origin

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