L5501

L-Lysine

≥98% (TLC)

• Synonym(s): (S)-2,6-Diaminocaproic acid
• Linear Formula: H₂N(CH₂)₄CH(NH₂)CO₂H
• CAS Number: 56-87-1
• Molecular Weight: 146.19
• Beilstein: 1722531
• EC Number: 200-294-2
• MDL number: MFCD00064433
• eCl@ss: 32160406
• PubChem Substance ID: 24896404
• NACRES: NA.26

Properties

• Quality Level: 200
• Assay: ≥98% (TLC)
• form: powder
• technique(s): ligand binding assay: suitable
• color: white to off-white
• mp: 215 °C (dec.) (lit.)
• solubility: H₂O: soluble
• SMILES string: NCCCC[C@H](N)C(O)=O
• InChI: 1S/C6H14N2O2/c7-4-2-1-3-5(8)6(9)10/h5H,1-4,7-8H2,(H,9,10)/t5-/m0/s1
• InChI key: KDXKERNSBIXSRK-YFKPBYRVSA-N

Description

General description

L-lysine contains basic side chain and is hydrophilic in nature. The N-butyl amino group in the side chain is found to be protonated at physiological pH. Upon degradation, L-lysine gives ketone bodies. Transamination of lysine with α-ketoglutarate produces acetoacetyl CoA. L-lysine serves as a precursor for secondary metabolites, such as β-lactam antibiotics. It also serves as a precursor for the biosynthesis of α-aminoadipic acid.

Application

L-Lysine is an essential proteinogenic α amino acid used in a wide range of applications. It has been used:

• as a supplement in cell culture media
• as a substrate for enzymes such as L-lysine oxidase (EC 1.4.3.14)
• as a component of poly-lysine polymers
• as a substrate for oxidation and glycation mechanism studies
• in the preparation of cobaltous lysine

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves