MSQC16

SILu^™Lite SigmaMAb Adalimumab Monoclonal Antibody

Name: SILu<SUP>™</SUP>Lite SigmaMAb Adalimumab Monoclonal Antibody
Brand: SIGMA
Price: 438 CAD

recombinant, expressed in CHO cells

Synonym(s):

Mass spectrometry standard, Adalimumab

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0.5 MG

$438.00

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About This Item

NACRES:

NA.84

UNSPSC Code:

41105331

Clone:

Species reactivity:

Application:

—

Citations:

Key Documents

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recombinant

expressed in CHO cells

assay

≥90% (SDS-PAGE)

form

solid

suitability

suitable for mass spectrometry

shipped in

wet ice

storage temp.

−20°C

Quality Level

100

Related Categories

Protein Biology

Protein Mass Spectrometry

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This Item	MSQC17	MSQC28	MSQC11
Sigma-Aldrich MSQC16 SILu^™Lite SigmaMAb Adalimumab Monoclonal Antibody	Sigma-Aldrich MSQC17 SILu^™Lite SigmaMAb Rituximab Monoclonal Antibody	Sigma-Aldrich MSQC28 SILu^™Lite SigmaMAb Vedolizumab Monoclonal Antibody	Sigma-Aldrich MSQC11 SILu^™MAb Adalimumab Stable-Isotope Labeled Monoclonal Antibody
storage temp. −20°C	storage temp. −20°C	storage temp. −20°C	storage temp. −20°C
form solid	form solid	form solid	form -
shipped in wet ice	shipped in wet ice	shipped in wet ice	shipped in wet ice
recombinant expressed in CHO cells	recombinant expressed in CHO cells	recombinant expressed in CHO cells	recombinant expressed in CHO cells
assay ≥90% (SDS-PAGE)	assay ≥90% (SDS-PAGE)	assay ≥90% (HPLC)	assay ≥90% (SDS-PAGE)
suitability suitable for mass spectrometry	suitability suitable for mass spectrometry	suitability suitable for mass spectrometry	suitability -

General description

SigmaMAb Adalimumab (MSQC16) was designed to be a standard for the analysis of Adalimumab monoclonal antibodies using mass spectrometry. An isotopically labeled version is available as SILu^™Mab Adalimumab (MSQC11).

SigmaMAb Adalimumab is for R&D use only. Not for drug, household, or other uses.

Other Notes

SigmaMab Adalimumab Heavy Chain:
EVQLVESGGGLVQPGRSLRLSCAASGFTFDDYAMHWVRQAPGKGLEWVSAITWNSGHIDYADSVEGRFTISRDNAKNSLYLQMNSLRAEDTAVYYCAKVSYLSTASSLDYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPG

SigmaMab Adalimumab Light Chain:
DIQMTQSPSSLSASVGDRVTITCRASQGIRNYLAWYQQKPGKAPKLLIYAASTLQSGVPSRFSGSGSGTDFTLTISSLQPEDVATYYCQRYNRAPYTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC

Legal Information

SILu is a trademark of Sigma-Aldrich Co. LLC

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Articles

Antibody Aggregates & Fragments Analysis Workflow

Characterize mAb monomers, aggregates, and fragments using SEC-UV workflow with Zenix^® and Zenix^®-C SEC columns.

Quality Attribute Determination of Monoclonal Antibodies

Workflows for monoclonal antibody adalimumab characterization ensure drug safety and efficacy through critical quality attribute analysis.

Protocols

Peptide Mapping LC-MS/MS Analysis Workflow for Adalimumab

An optimized LC-MS/MS based workflow for low artifact tryptic digestion and peptide mapping of monoclonal antibody, adalimumab (Humira) using filter assisted sample preparation (FASP).

Released N-Linked Glycan Analysis Workflow of Adalimumab

A step-by-step protocol for released N-linked glycan analysis of the monoclonal antibody adalimumab, based on UHPLC-FLR-MS and procainamide labeling.

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SILu^™Lite SigmaMAb Adalimumab Monoclonal Antibody