MSQC17

SILu^™Lite SigmaMAb Rituximab Monoclonal Antibody

Name: SILu<SUP>™</SUP>Lite SigmaMAb Rituximab Monoclonal Antibody
Brand: SIGMA
Price: 438 CAD

recombinant, expressed in CHO cells

Synonym(s):

Mass spectrometry standard, Rituximab

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0.5 MG

$438.00

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About This Item

NACRES:

NA.41

UNSPSC Code:

41105331

Clone:

Species reactivity:

Application:

—

Citations:

Key Documents

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form

solid

recombinant

expressed in CHO cells

assay

≥90% (SDS-PAGE)

suitability

suitable for mass spectrometry

shipped in

wet ice

storage temp.

−20°C

Quality Level

100

Related Categories

Protein Biology

Protein Mass Spectrometry

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This Item	MSQC18	MSQC20	MSQC13
Sigma-Aldrich MSQC17 SILu^™Lite SigmaMAb Rituximab Monoclonal Antibody	Sigma-Aldrich MSQC18 SILu^™Lite SigmaMAb Cetuximab Monoclonal Antibody	Sigma-Aldrich MSQC20 SILu^™Lite SigmaMAb Bevacizumab Monoclonal Antibody	Sigma-Aldrich MSQC13 SILu^™MAb Rituximab Stable-Isotope Labeled Monoclonal Antibody
shipped in wet ice	shipped in wet ice	shipped in wet ice	shipped in wet ice
storage temp. −20°C	storage temp. −20°C	storage temp. −20°C	storage temp. −20°C
form solid	form solid	form solid	form solid
recombinant expressed in CHO cells	recombinant expressed in CHO cells	recombinant expressed in CHO cells	recombinant expressed in CHO cells
assay ≥90% (SDS-PAGE)	assay ≥90% (SDS-PAGE)	assay ≥90% (SDS-PAGE)	assay ≥90% (SDS-PAGE)
suitability suitable for mass spectrometry	suitability suitable for mass spectrometry	suitability suitable for mass spectrometry	suitability suitable for mass spectrometry

General description

SigmaMAb Rituximab (MSQC17) was designed to be a standard for the analysis of Rituximab monoclonal antibodies using mass spectrometry. A heavy labeled version is available as SILu^™Mab Rituximab (MSQC13).

SigmaMAb Rituximab is for R&D use only. Not for drug, household, or other uses.

Application

SILu^™ Lite SigmaMAb Rituximab Monoclonal Antibody has been used to study its anticancer effects by antibody-dependent cell-mediated cytotoxicity (ADCC) mechanism.[1]

Other Notes

SigmaMab Rituximab Heavy Chain:
QVQLQQPGAELVKPGASVKMSCKASGYTFTSYNMHWVKQTPGRGLEWIGAIYPGNGDTSYNQKFKGKATLTADKSSSTAYMQLSSLTSEDSAVYYCARSTYYGGDWYFNVWGAGTTVTVSAASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKAEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPG

SigmaMab Rituximab Light Chain:
QIVLSQSPAILSASPGEKVTMTCRASSSVSYIHWFQQKPGSSPKPWIYATSNLASGVPVRFSGSGSGTSYSLTISRVEAEDAATYYCQQWTSNPPTFGGGTKLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC

Legal Information

SILu is a trademark of Sigma-Aldrich Co. LLC

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number

0000472051

0000421459

0000311029

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Recent advances in nanoscale materials for antibody-based cancer theranostics.

Deepak Kukkar et al.

Biosensors & bioelectronics, 173, 112787-112787 (2020-11-16)

The quest for advanced management tools or options of various cancers has been on the rise to efficiently reduce their risks of mortality without the demerits of conventional treatments (e.g., undesirable side effects of the medications on non-target tissues, non-targeted

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Fast assessment of antibody-dependent cell-mediated cytotoxicity (ADCC) and glycoform pattern of a therapeutic antibody rituximab by FcγRIIIa affinity chromatography.

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SILu^™Lite SigmaMAb Rituximab Monoclonal Antibody