MSQC20

SILu^™Lite SigmaMAb Bevacizumab Monoclonal Antibody

Name: SILu<SUP>™</SUP>Lite SigmaMAb Bevacizumab Monoclonal Antibody
Brand: SIGMA
Price: 576 CAD

recombinant, expressed in CHO cells

Synonym(s):

Mass spectrometry standard, Bevacizumab

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0.5 MG

$576.00

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About This Item

NACRES:

NA.41

UNSPSC Code:

12352203

Application:

—

Citations:

Key Documents

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recombinant

expressed in CHO cells

assay

≥90% (SDS-PAGE)

form

solid

suitability

suitable for mass spectrometry

shipped in

wet ice

storage temp.

−20°C

Related Categories

Protein Mass Spectrometry

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This Item	MSQC18	MSQC28	MSQC16
Sigma-Aldrich MSQC20 SILu^™Lite SigmaMAb Bevacizumab Monoclonal Antibody	Sigma-Aldrich MSQC18 SILu^™Lite SigmaMAb Cetuximab Monoclonal Antibody	Sigma-Aldrich MSQC28 SILu^™Lite SigmaMAb Vedolizumab Monoclonal Antibody	Sigma-Aldrich MSQC16 SILu^™Lite SigmaMAb Adalimumab Monoclonal Antibody
form solid	form solid	form solid	form solid
shipped in wet ice	shipped in wet ice	shipped in wet ice	shipped in wet ice
storage temp. −20°C	storage temp. −20°C	storage temp. −20°C	storage temp. −20°C
recombinant expressed in CHO cells	recombinant expressed in CHO cells	recombinant expressed in CHO cells	recombinant expressed in CHO cells
assay ≥90% (SDS-PAGE)	assay ≥90% (SDS-PAGE)	assay ≥90% (HPLC)	assay ≥90% (SDS-PAGE)
suitability suitable for mass spectrometry	suitability suitable for mass spectrometry	suitability suitable for mass spectrometry	suitability suitable for mass spectrometry

Application

SILu^™ Lite SigmaMAb Bevacizumab Monoclonal Antibody has been used as a proangiogenic factor to study its role in the angiogenesis process by Raman spectroscopy.

Biochem/physiol Actions

Bevacizumab serves as an antitumor agent. Studies show that chemotherapy using bevacizumab improves the condition of metastatic colorectal cancer and renal cell cancer patients.

General description

SigmaMAb Bevacizumab (MSQC20) was designed to be a standard for the analysis of Bevacizumab monoclonal antibodies using mass spectrometry. An isotopically labeled version is available as SILu^™Mab Bevacizumab (MSQC21).

SigmaMAb Bevacizumab is for R&D use only. Not for drug, household, or other uses.

Other Notes

SigmaMab Bevacizumab Heavy Chain:
EVQLVESGGGLVQPGGSLRLSCAASGYTFTNYGMNWVRQAPGKGLEWVGWINTYTGEPTYAADFKRRFTFSLDTSKSTAYLQMNSLRAEDTAVYYCAKYPHYYGSSHWYFDVWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPG

SigmaMab Bevacizumab Light Chain:
DIQMTQSPSSLSASVGDRVTITCSASQDISNYLNWYQQKPGKAPKVLIYFTSSLHSGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQQYSTVPWTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC

Legal Information

SILu is a trademark of Sigma-Aldrich Co. LLC

Storage Class

11 - Combustible Solids

wgk

WGK 3

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Certificates of Analysis (COA)

Lot/Batch Number

0000499629

0000466148

SLCM3376

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SILu^™Lite SigmaMAb Bevacizumab Monoclonal Antibody