MilliporeSigma
All Photos(3)

P3662

Sigma-Aldrich

Sodium pyruvate

Hybri-Max™, powder, suitable for hybridoma

All Photos(3)
Synonym(s):
α-Ketopropionic acid sodium salt, 2-Oxopropanoic acid sodium salt, Pyruvic acid sodium salt
Linear Formula:
CH3COCOONa
CAS Number:
113-24-6
Molecular Weight:
110.04
Beilstein:
3568341
EC Number:
204-024-4
MDL number:
MFCD00002586
PubChem Substance ID:
24898440
NACRES:
NA.75

biological source

synthetic (organic)

Quality Level

200

grade

Hybri-Max™

Assay

≥99%

form

powder

technique(s)

cell culture | hybridoma: suitable

impurities

endotoxin, tested

mp

>300 °C (lit.)

solubility

H2O: 100 mg/mL

shipped in

ambient

storage temp.

2-8°C

SMILES string

[Na+].CC(=O)C([O-])=O

InChI

1S/C3H4O3.Na/c1-2(4)3(5)6;/h1H3,(H,5,6);/q;+1/p-1

InChI key

DAEPDZWVDSPTHF-UHFFFAOYSA-M

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SAFC

105477

Sodium pyruvate

biological source

synthetic (organic)

biological source

-

biological source

-

biological source

synthetic

grade

Hybri-Max™

grade

-

grade

-

grade

-

form

powder

form

powder

form

powder

form

solid

technique(s)

cell culture | hybridoma: suitable

technique(s)

cell culture | embryo: suitable

technique(s)

cell culture | insect: suitable, cell culture | mammalian: suitable

technique(s)

-

impurities

endotoxin, tested

impurities

-

impurities

-

impurities

-

solubility

H2O: 100 mg/mL

solubility

H2O: 100 mg/mL

solubility

H2O: 100 mg/mL

solubility

-

Application

Sodium pyruvate has been used as a component in maturation medium for oocyte evaluation.
Sodium pyruvate is used by cells as an easily accessible carbohydrate source. Additionally, it is involved with amino acid metabolism and initiates the Kreb′s cycle. The 100 mM solution should be diluted 1:100 for most cell culture applications.

Biochem/physiol Actions

Sodium pyruvate is known to be an effective therapeutic target for type II citrullinaemia which is characterized by hyperammonaemia. In vivo studies proves that sodium pyruvate has protective function against hemorrhagic shock by preventing lipid peroxidation, NAD+ reduction and cleavage of poly(ADP-ribose) polymerases. Sodium pyruvate is also known to possess anti-inflammatory action and might show improvement in chronic lung disorder.

Legal Information

Hybri-Max is a trademark of Sigma-Aldrich Co. LLC

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H317 - H319

Hazard Classifications

Eye Irrit. 2 - Skin Sens. 1B

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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