PHG0007

MOPS

• Synonym(s): 3-(N-Morpholino)propanesulfonic acid, 4-Morpholinepropanesulfonic acid
• Empirical Formula (Hill Notation): C₇H₁₅NO₄S
• CAS Number: 1132-61-2
• Molecular Weight: 209.26
• Beilstein: 1106776
• EC Number: 214-478-5
• MDL number: MFCD00006183
• PubChem Substance ID: 329823025
• NACRES: NA.21

Properties

• biological source: synthetic
• Quality Level: 400
• assay: ≥99.5%
• form: powder
• technique(s): cell culture | mammalian: suitable
• impurities: Endotoxin, microbial, and trace metals; tested
• pH: 2.5-4 (1 M in H₂O)
• useful pH range: 6.5-7.9
• pKa (25 °C): 7.2
• λ: 1 M in H₂O
• suitability: suitable for manufacturing use
• foreign activity: Cytotoxicity, DNase, NICKase, RNase, and Protease; tested
• SMILES string: OS(=O)(=O)CCCN1CCOCC1
• InChI: 1S/C7H15NO4S/c9-13(10,11)7-1-2-8-3-5-12-6-4-8/h1-7H2,(H,9,10,11)
• InChI key: DVLFYONBTKHTER-UHFFFAOYSA-N

Description

Packaging

100 g in poly bottle

1 kg in poly bottle

10, 25 kg in poly drum

1 kit

Application

MOPS is a biological buffer also referred to as a “Propane Sultone” buffer. The pKa of MOPS is 7.01 which make it an ideal candidate for medias and protein based buffer formulations to maintain a stable environment in solution. MOPS is considered to be non-toxic to culture cell lines and provides high-solution clarity.

MOPS is used in cell culture media, biopharmaceutical buffer formulations (both upstream and downstream). MOPS based buffers are used in purification bioprocesses of antibodies, peptides, proteins and blood components.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): 230.0 °F - closed cup
• Flash Point(C): 110 °C - closed cup