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Key Documents

R4500

Sigma-Aldrich

(−)-Riboflavin

from Eremothecium ashbyii, ≥98%

Synonym(s):

Lactoflavin, Vitamin B2, Vitamin G

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5 G
$43.50
25 G
$53.20
100 G
$132.00
500 G
$487.00

About This Item

Empirical Formula (Hill Notation):
C17H20N4O6
CAS Number:
Molecular Weight:
376.36
Beilstein:
97825
EC Number:
MDL number:
UNSPSC Code:
12352205
eCl@ss:
34058005
PubChem Substance ID:
NACRES:
NA.79

$43.50


Estimated to ship onJune 23, 2025Details


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biological source

Eremothecium ashbyii

Quality Level

Assay

≥98%

form

powder

color

yellow to orange

mp

290 °C (dec.) (lit.)

storage temp.

room temp

SMILES string

CC1=C(C)C=C(N(C[C@H](O)[C@@H]([C@H](O)CO)O)C(C2=N3)=NC(NC2=O)=O)C3=C1

InChI

1S/C17H20N4O6/c1-7-3-9-10(4-8(7)2)21(5-11(23)14(25)12(24)6-22)15-13(18-9)16(26)20-17(27)19-15/h3-4,11-12,14,22-25H,5-6H2,1-2H3,(H,20,26,27)/t11-,12+,14-/m0/s1

InChI key

AUNGANRZJHBGPY-SCRDCRAPSA-N

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1 of 4

This Item
R9504V-067R7649
biological source

Eremothecium ashbyii

biological source

Eremothecium ashbyii

biological source

-

biological source

-

assay

≥98%

assay

≥98%

assay

-

assay

98.0-102.0% dry basis

form

powder

form

powder

form

liquid

form

powder

storage temp.

room temp

storage temp.

room temp

storage temp.

−20°C

storage temp.

-

mp

290 °C (dec.) (lit.)

mp

290 °C (dec.) (lit.)

mp

290 °C (dec.)

mp

290 °C (dec.) (lit.)

color

yellow to orange

color

yellow to orange

color

-

color

dark yellow

General description

Riboflavin belongs to the vitamin-B family and contains a pentose side chain ribitol.[1]

Application

Riboflavin has been used:
  • to check the role of riboflavin diet in rats[2]
  • as a supplement in HECM-6 medium (hamster embryo culture medium)[3]
  • as a supplement in the bacterial basal media[4]

Biochem/physiol Actions

Riboflavin is a key component of the redox cofactors flavin adenine dinucleotide (FAD) and flavin mononucleotide (FMN) that are used by a wide variety of flavoprotein oxidoreductases, dehydrogenase(s), decarboxylase(s) and electron transporters. Riboflavin is involved in various cellular processes, including β oxidation in lipid metabolism, glucose metabolism, protection from cellular oxidative injury, DNA and RNA metabolism, gluconeogenesis, erythropoiesis and generation of corticosteroids.[1] Riboflavin deficiency causes ariboflavinosis with symptoms such as sore throat, hyperemia, edema of oral and mucous membranes, cheilosis and glossitis.[5]

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

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Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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