Single-use and multi-use chromatography systems are critical factors for the successful separation of your valuable molecules. From pilot to process-scale, our systems are designed to provide robust, consistent performance with the processing flexibility you need. We also offer an unmatched portfolio of chromatography resins and membranes, backed by unparalleled applications and validation support. With this complete product offering, we continue to support you in your efforts to increase productivity and process efficiency. Our experts can help you find the right product for your chromatography process.
The Mobius® Multi Column Capture system is a fully automated, single-use solution to operate continuous closed capture chromatography. It manages process parameters in real time with reference to changing column load, surge feed tank load, and monitoring resin performance. Coupled with an in-line dilution capability and intuitive software, the 3 columns system allows complete control of the capture step of your fed-batch or perfusion bioprocess. The Mobius® Multi Column Capture system is suitable for bioreactor volumes ranging from 50 L to 2000 L.
The Mobius® Chrom 20 system is a flexible, fully automated, single-use chromatography system that enables consistent and reliable separation and purification of mAbs, vaccines, plasma, and therapeutic proteins at clinical and commercial scales. The innovative single-use flowpath reduces contamination risk while the flexible design features a standard hardware platform and options, empowering you to meet your unique process requirements. The Mobius® Chrom 20 system delivers optimal operational flexibility for a 2,000 L bioreactor scale, with flow rates from 0.4 L/min (isocratic mode) up to 20 L/min. In gradient mode the system covers flow rates from 4 L/min to 20 L/min, for a 5:1 turn down ratio, with unrivalled isocratic and linear gradient accuracy.
The Mobius® FlexReady Solution with Smart Flexware® Assemblies is a flexible system, allowing you to have a single, scalable system for chromatography. The fully automated system is designed to achieve separation and purification of mAbs, vaccines, plasma, and therapeutic proteins. The Mobius® FlexReady Solution with Smart Flexware® Assemblies delivers optimal operational flexibility in a very simple and fast way.
CoPrime® biochromatography systems are designed to achieve optimum separation and purification of monoclonal antibodies, vaccines, plasma, and therapeutic proteins. The systems support rapid scale-up and are ideally suited for pilot and process scale. They are based on 50 years of process knowledge and engineering expertise, providing a configurable, intuitive process-scale purification solution. CoPrime® B and C sizes have an extended flow rate span and optimized performance for greater gradient accuracy and purification reproduction. The CoPrime® size C covers higher scales and allows scale-up directly from CoPrime™ B.
Data Sheet: Mobius® Multi Column Capture System
Spare Parts List: Mobius® Multi Column Capture System
Application Note: Multi-Column Capture
Poster: Horizon 2020 - Fully Connected Single-use Downstream Platform for mAb Production
Data Sheet: Mobius® Chrom 20 System
Mobius® Chrom 20 System Spare Parts List
Video: Mobius® Chrom 20 System
For Purification of Biologics at Clinical and Process Scale
Purify your biologics at clinical and process scale, up to 2000 L. Learn how the Mobius® Chrom 20 System can optimize your purification process.
The benefits of a novel Protein A affinity membrane, used as a high productivity, truly single-use chromatography platform for intensified mAb purification
CEX flow-through frontal chromatography for the removal of mAb aggregates as well as the conditions that influence the removal of these aggregates.