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Liquid Visual Tests
Liquid Visual Tests
ABI3900 Synthesizer Columns with CUTAG CPG Frits
Next generation CPG Frit support for reliable, cost-effective oligo synthesis from Proligo®, for ABI 3900 and MerMade synthesizers
Calculators & Apps
Calculators & Apps
Press Release MilliporeSigma 0307 - NA
Press Release MilliporeSigma 0307 - NA
Dynamic Live Cell Imaging of Caspase Mediated Apoptosis and Cellular Hypoxia in Lymphocytes and Cancer Cells Using the CellASIC® ONIX2 Microfluidic Platform
Application note on how the CellASIC® ONIX2 microfluidic system can be used to analyze caspase-3 mediated apoptosis/cell death and cellular hypoxia in live immune and cancer cell lines.
Phosphorothioate Oligonucleotides
Phosphorothioate is a widely used backbone variant effective in creating oligonucleotides for antisense knockdowns.
Ago RIP to Isolate microRNA and their Targets Using Imprint® RNA Immunoprecipitation Kit
Sigma’s Imprint RNA Immunoprecipitation Kit was used to copurify human argonaute 2 (Ago2)-associated RNAs from HeLa cells. MicroRNAs reverse transcribed and quantitating using Mysticq reagents.
Development of a New Advanced KSOM Mouse Embryo Media that Enables Dual-Use Embryo Culture and Cell Handling Applications
Advanced KSOM mouse embryo media that can be used as a single medium for both harvest and culture of mouse embryos to facilitate creation of transgenic knockout mice.
CRISPR-based Gene Activation
Sigma has developed a gene activation system based on a fusion of dCas9 to the catalytic histone acetyltransferase (HAT) core domain of the human E1A-associated protein p300.
Genotypes, Phenotypes and Markers
A genotype is a list of mutant genes in an organism. In addition to mutations of the genome, other genetic elements such as prophage or plasmids can also be included.
LightCycler® Probes
LightCycler probes are highly sensitive and sequence-specific fluorescent probes designed for use with the Roche LightCycler instruments.
Fast siRNA
We can quickly synthesize and ship custom siRNA using your sequences.
Whole Transcriptome Amplification of RNA from Low Cell-Number Samples
The efficacy of amplification of small quantities of total RNA with the Complete Whole Transcriptome Amplification Kit (WTA2) was examined in this study.
Imprint ® DNA Modification Kit (MOD50) Protocol
The Imprint DNA Modification Kit provides the reagents needed for bisulfite conversion and post-modification clean-up of DNA samples in less than 2 hours.
PCR/qPCR Data Analysis
After a traditional PCR has been completed, the PCR/qPCR data analysis is conducted by resolution through an agarose gel or, more recently, through a capillary.
Oligonucleotide Quality Control by Mass Spectrometry
Mass Spectrometry is the technology of choice for analyzing oligonucleotide synthesis. It enables the most sensitive detection of low levels of by-products, which can affect performance.
Optimizing Crude Sample Plant PCR
Overcoming potent inhibitors and sample diversity in direct plant PCR.
3D Printing of Carbon Fiber-Reinforced Composites
3D printing is a type of additive manufacturing that can be used to rapidly fabricate components with highly customizable geometries.
Polymer Semiconductors for Intrinsically Stretchable Organic Transistors
Intrinsically stretchable active layers for organic field-effect transistors (OFET) are discussed. Polymer structural modification & post-polymerization modifications are 2 methods to achieve this.
Designing Temperature and pH Sensitive NIPAM Based Polymers
Poly(N-isopropylacrylamide), or PNIPAM, is a stimuli-responsive polymer that responds to changes in pH and temperature and has a LCST around 32 C.
Materials Design Concepts for Efficient Blue OLEDs: A Joint Theoretical and Experimental Study
Materials Design Concepts for Efficient Blue OLEDs: A Joint Theoretical and Experimental Study
3D Printable Conductive Nanocomposites of PLA and Multi-walled Carbon Nanotubes
A nanocomposite is typically defined as a mixture between a host material (e.g., polymer matrix) and nanofillers with at least one dimension of less than 100 nm.
Iscove's Modified Dulbecco's Media (IMDM) Formulation
Iscove's Modified Dulbecco's Media (IMDM) Formulation
L-15 Media Formulation
L-15 Media Formulation
Accelerated Osteocyte Differentiation of Human Mesenchymal Stem Cells in a Novel Xeno-free and Serum-free Osteogenesis Differentiation Media
Development of a novel serum-free and xeno-free human mesenchymal stem cell (MSC) osteocyte differentiation media.
Utilization of TrueGel3D™ Hydrogels to Study Fibroblast Spreading
Fibroblasts that are present in the stroma secrete glycoproteins and polysaccharides to form extracellular matrix. They maintain the structural integrity within the connective tissue and play a key role in cancer, chronic obstructive pulmonary diseases, idiopathic pulmonary fibrosis, scleroderma and
NCTC 109 Medium Formulation
NCTC 109 Medium Formulation
3D Neurosphere Culture Media
3D neurosphere culture protocol to expand human U-87 MG glioblastoma cells in serum-free/xeno-free stem cell culture media. Explore over 350 PromoCell products on Sigma.com.
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