SILu™ Lite SigmaMAb

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LC-UV-MS Method Development for Antibody Drug Conjugates Using a Non-Toxic ADC-Mimic

SigmaMab Antibody Drug Conjugate Mimic, is a non-toxic drug mimic utilized as a standard for mass spectrometry and high performance liquid chromatography.

Quantification of Host Cell Proteins

Residual presence of host cell proteins (HCPs) in recombinant therapeutic products has considerable clinical safety risks associated with a potential immunological response in patients.

Antibody Drug Conjugate Mimic Enables LC-MS Method Development Without Risk

Here we show how LC and MS methods may be optimized using a non-toxic surrogate of the ADC, an “ADC-mimic”, that behaves very similarly to the Cys-linked ADC Adcetris (Seattle Genetics).

Selectfluor™

Selectfluor™ (F-TEDA) is a mild, stable reagent for electrophilic fluorination, enhancing user-friendly fluorination reactions.

KiCqStart™ Probe qPCR ReadyMix™

KiCqStart™ Probe qPCR ReadyMix™ is an advanced qPCR reagent system for both fast and conventional PCR cycling protocols or instruments.

ProClin™ Preservatives

Discover ProClin™ preservatives: extend IVD reagent shelf life, inhibit microbes effectively, and ensure safety with no health or disposal concerns.

SMCxPRO™ Immunoassay Instrument and SMC™ Kits

High Sensitivity Protein Measurement at the fg/mL level Synonym: SMC, Singulex, single molecule counting, xPRO

Live Cell Imaging of Autophagy with LentiBrite™

HT-1080 cells transduced with LentiBrite™ GFP-LC3 lentiviral particles induce autophagy, aiding research in cellular processes.

Astec CYCLOBOND™

CYCLOBOND is the name given to Astec technology for bonding cyclodextrins to a high purity silica gel through a stable ether linkage.

PhosSTOP™ Protocol

The phosphatase inhibitors included in PhosSTOP Tablets can be deactivated or removed from a lysate using dialysis.

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