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MilliporeSigma

CAV1

caveolin 1, caveolae protein, 22kDa

Synonymes:
BSCL3, CGL3, MSTP085, PPH3, VIP21
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(857) Summary: The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in this gene have been associated with Berardinelli-Seip congenital lipodystrophy. Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1.[provided by RefSeq, Mar 2010]
  • Mouse(12389) caveolin 1, caveolae protein
  • Rat(25404) caveolin 1, caveolae protein
  • naked mole-rat(101726366) caveolin 1, caveolae protein, 22kDa
  • domestic guinea pig(100718512) caveolin 1, caveolae protein, 22kDa
  • chicken(373996) caveolin 1, caveolae protein, 22kDa
  • dog(403980) caveolin 1, caveolae protein, 22kDa
  • domestic cat(493668) caveolin 1, caveolae protein, 22kDa
  • Horse(100055975) caveolin 1, caveolae protein, 22kDa
  • Goat(100860749) caveolin 1, caveolae protein, 22kDa
  • cow(281040) caveolin 1, caveolae protein, 22kDa
  • sheep(445468) caveolin 1, caveolae protein, 22kDa
  • Domestic Rabbit(100008837) caveolin 1, caveolae protein, 22kDa
  • domestic guinea pig(100135639) caveolin 1, caveolae protein
  • Zebrafish(323695) caveolin 1

Custom & Knockdown Gene Products

Antibodies

Numéro du produit
Description
Espèces réactives
Application
Anti-CAV1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
western blot
Anti-CAV1 antibody produced in rabbit, purified antibody, Protein A purified,
Espèces réactives
bovine, dog, horse, human, mouse, pig, rabbit, rat, sheep
Application
immunohistochemistry
western blot
Anti-Caveolin-1 antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse, rat
Application
ELISA
immunofluorescence

western blot
Anti-CAV1 (Ab-14) antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse, rat
Application
western blot
Anti-phospho-Caveolin-1 (Ser37), from rabbit, purified by affinity chromatography,
Espèces réactives
human, mouse, rat
Application
inhibition assay
western blot

esiRNA

Numéro du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human CAV1,
Espèce(s)
human
MISSION® esiRNA, targeting mouse Cav1,
Espèce(s)
mouse