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CD74

CD74 molecule, major histocompatibility complex, class II invariant chain

Synonymes:
DHLAG, HLADG, II, Ia-GAMMA
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(972) Summary: The protein encoded by this gene associates with class II major histocompatibility complex (MHC) and is an important chaperone that regulates antigen presentation for immune response. It also serves as cell surface receptor for the cytokine macrophage migration inhibitory factor (MIF) which, when bound to the encoded protein, initiates survival pathways and cell proliferation. This protein also interacts with amyloid precursor protein (APP) and suppresses the production of amyloid beta (Abeta). Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]
  • Mouse(16149) CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)
  • Rat(25599) Cd74 molecule, major histocompatibility complex, class II invariant chain
  • cow(613384) CD74 molecule, major histocompatibility complex, class II invariant chain
  • domestic cat(101085953) CD74 molecule, major histocompatibility complex, class II invariant chain
  • domestic guinea pig(100735496) CD74 molecule, major histocompatibility complex, class II invariant chain
  • dog(479329) CD74 molecule, major histocompatibility complex, class II invariant chain
  • sheep(101102561) CD74 molecule, major histocompatibility complex, class II invariant chain
  • chicken(414741) CD74 molecule, major histocompatibility complex, class II invariant chain
  • naked mole-rat(101723625) CD74 molecule, major histocompatibility complex, class II invariant chain

Custom & Knockdown Gene Products

ELISA

Numéro du produit
Description
Espèce(s)
Human CD74 ELISA, for serum, plasma and cell culture supernatants,
Espèce(s)
human

Antibodies

Numéro du produit
Description
Espèces réactives
Application
Anti-CD74 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
western blot
Anticorps anti-CMH de classe II (I-A/I-E), clone M5/114, clone M5/114, from rat,
Espèces réactives
mouse
Application
flow cytometry
immunohistochemistry

western blot
Anti-MHC class II (I-A/I-E), redFluor® 710, clone M5/114 .15.2 Antibody, clone M5/114.15.2, from rat, redFluor® 710,
Espèces réactives
mouse
Application
flow cytometry
Anti-MHC class II (I-A/I-E), violetFluor® 450, clone M5/114 .15.2 Antibody, clone M5/114.15.2, from rat, violetFluor® 450,
Espèces réactives
mouse
Application
flow cytometry
Anti-MHC class II (I-A/I-E), PE, clone M5/114 .15.2 Antibody, clone M5/114.15.2, from rat, PE,
Espèces réactives
mouse
Application
flow cytometry

esiRNA

Numéro du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human CD74,
Espèce(s)
human
MISSION® esiRNA, targeting mouse Cd74,
Espèce(s)
mouse