KDR
kinase insert domain receptor (a type III receptor tyrosine kinase)
Synonymes:
CD309, FLK1, VEGFR, VEGFR2
Espèce(s):
Human KDR (3791), Mouse Kdr (16542), Rat Kdr (25589), chicken KDR (395323), Zebrafish kdr (554230), Thale Cress KDR (839585), dog KDR (482154), Goat KDR (100860836), cow KDR (407170), Horse KDR (100033959) ...Plus
ID UniProtKB:
ID du gène:
- Human(3791) Summary: Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas. [provided by RefSeq, May 2009]
- Mouse(16542) kinase insert domain protein receptor
- Rat(25589) kinase insert domain receptor
- chicken(395323) kinase insert domain receptor (a type III receptor tyrosine kinase)
- Zebrafish(554230) kinase insert domain receptor (a type III receptor tyrosine kinase)
- Thale Cress(839585) basic helix-loop-helix protein KIDARI
- dog(482154) kinase insert domain receptor (a type III receptor tyrosine kinase)
- Goat(100860836) kinase insert domain receptor (a type III receptor tyrosine kinase)
- cow(407170) kinase insert domain receptor (a type III receptor tyrosine kinase)
- Horse(100033959) kinase insert domain receptor (a type III receptor tyrosine kinase)
- domestic cat(101090260) kinase insert domain receptor (a type III receptor tyrosine kinase)
- Domestic Rabbit(100008607) kinase insert domain receptor (a type III receptor tyrosine kinase)
- sheep(443087) vascular endothelial growth factor receptor-2
- naked mole-rat(101726029) kinase insert domain receptor (a type III receptor tyrosine kinase)
- domestic guinea pig(100726761) kinase insert domain receptor (a type III receptor tyrosine kinase)
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ELISA
Antibodies
Numéro du produit
Description
Espèces réactives
Application
Anti-phospho-VEGFR2 (pTyr1175) antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse, rat
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-VEGFR2 antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Monoclonal Anti-Vascular Endothelial Growth Factor Receptor-2 antibody produced in mouse, clone KDR-1, ascites fluid,
Espèces réactives
human
Application
ELISA
immunohistochemistry
immunohistochemistry
Anti-Vascular Endothelial Growth Factor Receptor 2 antibody produced in goat, affinity isolated antibody, lyophilized powder,
Espèces réactives
mouse
Application
flow cytometry
immunohistochemistry
neutralization
western blot
immunohistochemistry
neutralization
western blot
Anti-VEGFR2 antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse, rat
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Small Molecule - Inhibitor
Numéro du produit
Description
Espèce(s)
7-Cyclopentyl-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3‑d]pyrimidin-4-ylamine, ≥98% (HPLC),
Espèce(s)
human
Proteins
Numéro du produit
Description
Espèce(s)
KDR Protein, active, 10 µg, Active, N-terminal His6-tagged, recombinant, human KDR amino acids 790-end,
for use in Kinase Assays.,
for use in Kinase Assays.,
Espèce(s)
human
VEGF Receptor-2 (Flk-1, KDR)/Fc Chimera human, >90% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder,
Espèce(s)
human