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PTS

6-pyruvoyltetrahydropterin synthase

Synonymes:
PTPS
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(5805) Summary: The enzyme encoded by this gene catalyzes the elimination of inorganic triphosphate from dihydroneopterin triphosphate, which is the second and irreversible step in the biosynthesis of tetrahydrobiopterin from GTP. Tetrahydrobiopterin, also known as BH(4), is an essential cofactor and regulator of various enzyme activities, including enzymes involved in serotonin biosynthesis and NO synthase activity. Mutations in this gene result in hyperphenylalaninemia. [provided by RefSeq, Oct 2008]
  • Mouse(19286) 6-pyruvoyl-tetrahydropterin synthase
  • Rat(29498) 6-pyruvoyl-tetrahydropterin synthase
  • fruit fly(252458) ponte thermosensible
  • Zebrafish(100073330) 6-pyruvoyltetrahydropterin synthase
  • chicken(374144) 6-pyruvoyltetrahydropterin synthase
  • dog(611326) 6-pyruvoyltetrahydropterin synthase
  • domestic cat(101096347) 6-pyruvoyltetrahydropterin synthase
  • cow(506860) 6-pyruvoyltetrahydropterin synthase
  • sheep(101108950) 6-pyruvoyltetrahydropterin synthase
  • domestic guinea pig(100733894) 6-pyruvoyltetrahydropterin synthase
  • naked mole-rat(101705212) 6-pyruvoyltetrahydropterin synthase

Custom & Knockdown Gene Products

Antibodies

Numéro du produit
Description
Espèces réactives
Application
Anti-PTS antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
immunohistochemistry

western blot
Anti-phospho-PTS (Ser19) Antibody, clone 24GB800, Rabbit Monoclonal, clone 24GB800, recombinant rabbit monoclonal, expressed in HEK293 cells,
Espèces réactives
human, rat
Application
flow cytometry
immunofluorescence

western blot

esiRNA

Numéro du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human PTS,
Espèce(s)
human
MISSION® esiRNA, targeting mouse Pts,
Espèce(s)
mouse