RET
ret proto-oncogene
Synonymes:
CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET-ELE1, RET51
Espèce(s):
Human RET (5979), Mouse Ret (19713), Rat Ret (24716), Zebrafish ret (30512), fruit fly ret (44319), fruit fly Ret (43875), chicken RET (396107), dog RET (403494), Horse RET (100033966), domestic cat RET (101101086) ...Plus
ID UniProtKB:
ID du gène:
- Human(5979) Summary: This gene, a member of the cadherin superfamily, encodes one of the receptor tyrosine kinases, which are cell-surface molecules that transduce signals for cell growth and differentiation. This gene plays a crucial role in neural crest development, and it can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Mutations in this gene are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine neoplasia, type IIB, Hirschsprung disease, and medullary thyroid carcinoma. Two transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described but their biological validity has not been confirmed. [provided by RefSeq, Jul 2008]
- Mouse(19713) ret proto-oncogene
- Rat(24716) ret proto-oncogene
- Zebrafish(30512) ret proto-oncogene receptor tyrosine kinase
- fruit fly(44319) reticulated
- fruit fly(43875) Ret oncogene
- chicken(396107) ret proto-oncogene
- dog(403494) ret proto-oncogene
- Horse(100033966) ret proto-oncogene
- domestic cat(101101086) ret proto-oncogene
- cow(515924) ret proto-oncogene
- Domestic Rabbit(100340710) ret proto-oncogene
- sheep(101119787) ret proto-oncogene
- naked mole-rat(101717565) ret proto-oncogene
- domestic guinea pig(100733392) ret proto-oncogene
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ELISA
Antibodies
Numéro du produit
Description
Espèces réactives
Application
Anti-phospho-Ret (pTyr1062) antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse, rat
Application
ELISA
western blot
western blot
Anti-RET antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-RET Antibody, clone 2K12 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Espèces réactives
human, monkey, mouse
Application
immunocytochemistry
immunohistochemistry
western blot
immunohistochemistry
western blot
Monoclonal Anti-RET antibody produced in mouse, clone 1A5, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
ELISA
proximity ligation assay
western blot
proximity ligation assay
western blot
Monoclonal Anti-RET antibody produced in mouse, clone 8D10C9, ascites fluid,
Espèces réactives
human
Application
ELISA
western blot
western blot
Small Molecule - Inhibitor
Numéro du produit
Description
Espèce(s)
Proteins
Numéro du produit
Description
Espèce(s)
Ret (V804M) Protein, active, 10 µg, Active, N-Terminal GST-tagged, recombinant, human Ret amino acids 658 – end containing the V804M mutation. For use in Kinase Assays.,
Espèce(s)
human
Ret Protein, active, 10 µg, Active, N-Terminal GST-tagged, recombinant, human Ret amino acids 658-end, for use in Kinase Assays.,
Espèce(s)
human
Ret (V804L) Protein, active, 10 µg, Active, N-Terminal GST-tagged, recombinant, human Ret amino acids 658 – end containing the V804L mutation. For use in Kinase Assays.,
Espèce(s)
human
RET (V804L), active, GST tagged human, PRECISIO®, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Espèce(s)
human