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P2066

Poly(D,L-lactide-co-glycolide)

lactide:glycolide 65:35, Mw 40,000-75,000

Synonyme(s) :

Lactel® B6001-1, PLGA

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À vous/RéférenceDisponibilitéPrix
1 g
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133,00 $
5 g
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438,00 $

A propos de cet article

Formule linéaire :
[C3H4O2]x[C2H2O2]y
UNSPSC Code:
12162002
PubChem Substance ID:
NACRES:
NA.23
MDL number:

133,00 $


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form

pellets

Quality Segment

feed ratio

lactide:glycolide 65:35

mol wt

Mw 40,000-75,000

storage temp.

−20°C

SMILES string

OCC(O)=O.CC(O)C(O)=O

InChI

1S/C3H6O3.C2H4O3/c1-2(4)3(5)6;3-1-2(4)5/h2,4H,1H3,(H,5,6);3H,1H2,(H,4,5)

InChI key

XBBVURRQGJPTHH-UHFFFAOYSA-N

Application


  • Inhaled Macrophage Apoptotic Bodies-Engineered Microparticle Enabling Construction of Pro-Regenerative Microenvironment to Fight Hypoxic Lung Injury in Mice.: This study demonstrates the use of Poly(ᴅ,ʟ-lactide-co-glycolide) (PLGA) in engineering microparticles that promote lung tissue regeneration in hypoxic conditions, highlighting its potential in developing advanced therapeutic strategies for respiratory injuries (Liu et al., 2024).

  • Engineered nanoparticles promote cardiac tropism of AAV vectors.: The research explores the role of PLGA nanoparticles in enhancing the targeting efficiency of AAV vectors to cardiac tissues, showcasing its application in gene therapy and cardiovascular disease treatment (Switala et al., 2024).

  • Drug-loaded adhesive microparticles for biofilm prevention on oral surfaces.: This article reports the development of drug-loaded PLGA microparticles designed to prevent biofilm formation on oral surfaces, demonstrating the polymer′s utility in dental applications and biofilm-associated infections (Oh et al., 2024).

  • Dual-layer conduit containing VEGF-A - Transfected Schwann cells promotes peripheral nerve regeneration via angiogenesis.: PLGA-based dual-layer conduits are utilized to support nerve regeneration by enhancing angiogenesis, indicating its importance in neuroregenerative medicine and peripheral nerve injury treatments (Huang et al., 2024).

  • Application of Doxorubicin-loaded PLGA nanoparticles targeting both tumor cells and cancer-associated fibroblasts on 3D human skin equivalents mimicking melanoma and cutaneous squamous cell carcinoma.: The study highlights the dual-targeting capability of PLGA nanoparticles in delivering chemotherapy drugs to both tumor cells and the surrounding supportive stroma, emphasizing its role in advanced cancer therapies (He et al., 2024).

Features and Benefits

Controlled release of bioactive agents, sutures and bioabsorbable implantable devices.

Physical form

Biocompatible, biodegradable polymer.

Legal Information

Lactel is a registered trademark of Evonik Corp

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Cet article
P1566806358802182
description

lactide:glycolide 65:35, Mw 40,000-75,000

description

mol wt 85,000-160,000

description

lactide:glycolide 75:25, Mw 6,000-10,000

description

lactide:glycolide (50:50), ester terminated, average Mw 100,000

form

pellets

form

pellets

form

pellets

form

solid

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

2-8°C

Quality Level

100

Quality Level

200

Quality Level

100

Quality Level

100

feed ratio

lactide:glycolide 65:35

feed ratio

-

feed ratio

-

feed ratio

lactide:glycolide (50:50)

mol wt

Mw 40,000-75,000

mol wt

85,000-160,000

mol wt

Mw 6,000-10,000

mol wt

average Mw 100,000


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Classe de stockage

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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