ACVR2B
activin A receptor, type IIB
Synonyme:
ACTRIIB, ActR-IIB, HTX4
Spezies:
Human ACVR2B (93), Mouse Acvr2b (11481), Rat Acvr2b (25366), Horse ACVR2B (100053588), domestic cat ACVR2B (101086087), dog ACVR2B (485590), naked mole-rat Acvr2b (101711703), Zebrafish acvr2b (30457), chicken ACVR2B (374213), domestic guinea pig Acvr2b (100722791) ...Mehr
UniProtKB-ID:
Gen-ID:
- Human(93) Summary: Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases. This gene encodes activin A type IIB receptor, which displays a 3- to 4-fold higher affinity for the ligand than activin A type II receptor. [provided by RefSeq, Jul 2008]
- Mouse(11481) activin receptor IIB
- Rat(25366) activin A receptor, type IIB
- Horse(100053588) activin A receptor, type IIB
- domestic cat(101086087) activin A receptor, type IIB
- dog(485590) activin A receptor, type IIB
- naked mole-rat(101711703) activin A receptor, type IIB
- Zebrafish(30457) activin receptor IIb
- chicken(374213) activin A receptor, type IIB
- domestic guinea pig(100722791) activin A receptor, type IIB
- sheep(443156) activin A receptor, type IIB
- cow(282131) activin A receptor, type IIB
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ELISA
Produktnummer
Beschreibung
Spezies
Antibodies
Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti ACVR2B Antibody, clone 23GB620, Rabbit Monoclonal, clone 23GB620, recombinant rabbit monoclonal, expressed in HEK293 cells,
Speziesreaktivität
human, rat
Anwendung
immunofluorescence
western blot
western blot
Anti-Activin Receptor IIB antibody produced in goat, affinity isolated antibody,
Speziesreaktivität
human
Anwendung
flow cytometry
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-ACVR2B antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
bovine, dog, guinea pig, horse, human, rat, sheep
Anwendung
western blot
Monoclonal Anti-ACVR2B antibody produced in mouse, clone 1C11, purified immunoglobulin, buffered aqueous solution,
Speziesreaktivität
human
Anwendung
ELISA
western blot
western blot
Anti-ACVR2B (C-terminal) antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
human
Anwendung
western blot