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Merck

KIT

v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog

Synonyme:
C-Kit, CD117, PBT, SCFR
Spezies:
Human KIT (3815), Mouse Kit (16590), Rat Kit (64030), Domestic Rabbit KIT (100327263), dog KIT (403811), domestic cat KIT (493766), Horse KIT (100009704), cow KIT (280832), Goat KIT (100861386), sheep KIT (780504) ...Mehr
UniProtKB-ID:
P10721, B5A956, D5LXN2, D5M931, F5H8F8, Q6IQ28, Q99662, Q9UM99
Gen-ID:
  • Human(3815) Summary: This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(16590) kit oncogene
  • Rat(64030) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • Domestic Rabbit(100327263) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • dog(403811) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • domestic cat(493766) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • Horse(100009704) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • cow(280832) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • Goat(100861386) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • sheep(780504) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • chicken(378783) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • domestic guinea pig(100726397) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • naked mole-rat(101726400) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog

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ELISA

Produktnummer
Beschreibung
Spezies
RAB0731
Human KIT / Mast/Stem Cell Growth Factor Receptor Kit ELISA Kit, ,
Spezies
human
RAB0992
Phosphotyrosine KIT / Mast/stem Cell Growth Factor Receptor Kit ELISA Kit, ,
Spezies
human

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
MABF511
Anti-CD117 (c-Kit) Antibody (mouse), PE, clone ACK2, clone ACK2, 0.2 mg/mL, from rat,
Speziesreaktivität
mouse
Anwendung
flow cytometry
immunocytochemistry
immunohistochemistry
ZRB3201
Anti-c-Kit/CD117 Antibody, clone 1I8 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Speziesreaktivität
human
Anwendung
affinity binding assay
immunohistochemistry
western blot
MABF361
Anti-CD117 (c-kit) Antibody (mouse), PE, clone ACK2, clone ACK2, 0.2 mg/mL, from rat,
Speziesreaktivität
mouse
Anwendung
flow cytometry
immunocytochemistry
immunohistochemistry
SAB4501648
Anti-C-KIT antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
human, mouse, rat
Anwendung
ELISA
western blot
MABF360
Anti-CD117 (c-kit) Antibody (mouse), APC, clone ACK2, clone ACK2, 0.2 mg/mL, from rat,
Speziesreaktivität
mouse
Anwendung
flow cytometry
immunocytochemistry
immunohistochemistry
western blot

Small Molecule - Inhibitor

Produktnummer
Beschreibung
Spezies
CDS022173
Imatinib, ,
Spezies
human
CDS023580
Pazopanib, ,
Spezies
human
SML2589
Dasatinib, ≥98% (HPLC),
Spezies
human
CDS023389
Dasatinib, ,
Spezies
human

Proteins

Produktnummer
Beschreibung
Spezies
14-611-M
c-Kit (D816V) Protein, active, 10 µg, Active, N-terminal GST tagged, recombinant human c-Kit, amino acids 544-end containing the D816V mutation, for use in Kinase Assays.,
Spezies
human
14-559-M
c-Kit Protein, active, 10 µg, Active, N-terminal GST tagged, recombinant, human Kit, amino acids 544-end, for use in Kinase Assays.,
Spezies
human
SRP0342
cKit active human, recombinant, expressed in baculovirus infected Sf9 cells, ≥32% (SDS-PAGE),
Spezies
human
SRP5300
c-KIT (N822K), active, GST tagged human, PRECISIO®, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Spezies
human
C0499
c-KIT (544-end, V654A), active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Spezies
human

esiRNA

Produktnummer
Beschreibung
Spezies
EHU000841
MISSION® esiRNA, targeting human KIT,
Spezies
human
EMU049661
MISSION® esiRNA, targeting mouse Kit,
Spezies
mouse