Direkt zum Inhalt
Merck

SRC

v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog

Synonyme:
ASV, SRC1, c-SRC, p60-Src
Spezies:
Human SRC (6714), Mouse Src (20779), Rat Src (83805), Zebrafish src (325084), chicken SRC (396442), domestic cat SRC (101100378), dog SRC (485864), sheep SRC (101103084), cow SRC (535742), domestic guinea pig Src (100728509)
UniProtKB-ID:
P12931, E1P5V4, Q76P87, Q86VB9, Q9H5A8
Gen-ID:
  • Human(6714) Summary: This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(20779) Rous sarcoma oncogene
  • Rat(83805) v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog
  • Zebrafish(325084) v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
  • chicken(396442) v-src sarcoma viral oncogene
  • domestic cat(101100378) v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
  • dog(485864) v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
  • sheep(101103084) v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
  • cow(535742) v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
  • domestic guinea pig(100728509) Rous sarcoma oncogene
  • naked mole-rat(101703827) v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Small Molecule - Antagonist

Produktnummer
Beschreibung
Spezies
695017
Phosphorsäure, ACS reagent, ≥85 wt. % in H2O,
Spezies
human
438081
Phosphorsäure, ACS reagent, ≥85 wt. % in H2O,
Spezies
human
27109
Zitronensäure, meets analytical specification of Ph. Eur., BP, USP, E330, anhydrous, 99.5-100.5% (based on anhydrous substance),
Spezies
human
345245
Phosphorsäure, 85 wt. % in H2O, 99.99% trace metals basis,
Spezies
human
251275
Zitronensäure, ACS reagent, ≥99.5%,
Spezies
human

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
SAB6012515
KD-Validated Anti-phospho-Src (Tyr419) Antibody, clone 23GB4080, Rabbit Monoclonal, clone 23GB4080, recombinant rabbit monoclonal, expressed in HEK293 cells,
Speziesreaktivität
human, rat
Anwendung
flow cytometry
western blot
SAB6012526
KD-Validated Anti-phospho-Src (Tyr529) Antibody, clone 23GB6690, Rabbit Monoclonal, clone 23GB6690, recombinant rabbit monoclonal, expressed in HEK293 cells,
Speziesreaktivität
human, rat
Anwendung
western blot
SAB6012539
KD-Validated Anti Src Antibody, clone 23GB1110, Rabbit Monoclonal, clone 23GB1110, recombinant rabbit monoclonal, expressed in HEK293 cells,
Speziesreaktivität
human, rat
Anwendung
flow cytometry
immunofluorescence
western blot
SAB6012540
KD-Validated Anti Src Antibody, clone 23GB985, Rabbit Monoclonal, clone 23GB985, recombinant rabbit monoclonal, expressed in HEK293 cells,
Speziesreaktivität
human, rat
Anwendung
flow cytometry
immunofluorescence
western blot
SAB6012542
KD-Validated Anti Src Antibody, clone 23GB980, Rabbit Monoclonal, clone 23GB980, recombinant rabbit monoclonal, expressed in HEK293 cells,
Speziesreaktivität
human, rat
Anwendung
flow cytometry
immunofluorescence
western blot

Small Molecule - Inhibitor

Produktnummer
Beschreibung
Spezies
S9692
SU 6656, ≥98% (HPLC),
Spezies
human
R2146
Radicicol from Diheterospora chlamydosporia, solid,
Spezies
human, rat
E2250
Ellagsäure, ≥95% (HPLC), powder, from tree bark,
Spezies
human, rat
T182
Tyrphostin A9, solid,
Spezies
mouse, human
SML2589
Dasatinib, ≥98% (HPLC),
Spezies
human

Kits

Produktnummer
Beschreibung
Spezies
20-121
Src Kinase Reaction Buffer, ,
Spezies
human

Proteins

Produktnummer
Beschreibung
Spezies
S1076
SRC, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in E. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Spezies
human
14-326-M
Src Protein, active, 10 µg, Active, N-Terminal His6-tagged, recombinant, full-length, human Src. For use in Kinase Assays.,
Spezies
human
14-746-M
Src (1-530) Protein, active, 10 µg, ,
Spezies
human
14-748-M
Src (T341M) Protein, active, 10 µg, Active, N-terminal 6His-tagged, recombinant, full-length human Src, containing the T341M mutation. For use in Kinase Assays.,
Spezies
human
S5564
SRC N1 human, ≥60% (SDS-PAGE), recombinant, expressed in baculovirus infected insect cells, buffered aqueous glycerol solution,
Spezies
human

esiRNA

Produktnummer
Beschreibung
Spezies
EMU071351
MISSION® esiRNA, targeting mouse Src,
Spezies
mouse

Small Molecule - Substrate

Produktnummer
Beschreibung
Spezies
12-140
Src Substrate Peptide, Src Substrate Peptide primarily used in Kinase Assays.,
Spezies
human