STAT6
signal transducer and activator of transcription 6, interleukin-4 induced
Synonyme:
D12S1644, IL-4-STAT, STAT6B, STAT6C
Spezies:
Human STAT6 (6778), Mouse Stat6 (20852), Rat Stat6 (362896), domestic cat STAT6 (101089873), chicken STAT6 (100859196), dog STAT6 (100142679), sheep STAT6 (101102134), cow STAT6 (353105), Horse STAT6 (100050053), Zebrafish stat6 (337413) ...Mehr
UniProtKB-ID:
Gen-ID:
- Human(6778) Summary: The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
- Mouse(20852) signal transducer and activator of transcription 6
- Rat(362896) signal transducer and activator of transcription 6, interleukin-4 induced
- domestic cat(101089873) signal transducer and activator of transcription 6, interleukin-4 induced
- chicken(100859196) signal transducer and activator of transcription 6, interleukin-4 induced
- dog(100142679) signal transducer and activator of transcription 6, interleukin-4 induced
- sheep(101102134) signal transducer and activator of transcription 6, interleukin-4 induced
- cow(353105) signal transducer and activator of transcription 6, interleukin-4 induced
- Horse(100050053) signal transducer and activator of transcription 6, interleukin-4 induced
- Zebrafish(337413) signal transducer and activator of transcription 6, interleukin-4 induced
- domestic guinea pig(100726686) signal transducer and activator of transcription 6, interleukin-4 induced
- naked mole-rat(101725744) signal transducer and activator of transcription 6, interleukin-4 induced
- Domestic Rabbit(100344264) signal transducer and activator of transcription 6, interleukin-4 induced
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ELISA
Produktnummer
Beschreibung
Spezies
Phosphotyrosine STAT6 / Signal Transducer and Activator of Transcription 6 ELISA Kit, ,
Spezies
human
Cell-Based ELISA for detecting phospho-STAT6 (pTyr641) in cultured cell lines, 96 assays,
Spezies
mouse, human
Cell-Based phospho-STAT ELISA Samper Kit for detecting phospho-STAT1 (pTyr701), phospho-STAT3 (pTyr705), and phospho-STAT5 (pTyr694) in cultured cell lines, 192 assays,
Spezies
mouse, rat, human
Antibodies
Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-STAT6 Antibody, clone 1C13 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Speziesreaktivität
human, monkey
Anwendung
affinity binding assay
flow cytometry
immunohistochemistry
western blot
flow cytometry
immunohistochemistry
western blot
Anti-STAT6 antibody produced in rabbit, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-phospho-STAT6 (Tyr641) Antibody, clone 16E12, clone 16E12, Upstate®, from mouse,
Speziesreaktivität
human, mouse, rat
Anwendung
western blot
Anti-phospho-STAT6 (Tyr641) Antibody, Upstate®, from rabbit,
Speziesreaktivität
human, mouse
Anwendung
western blot
Anti-phospho-STAT6 (pTyr641) antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
human
Anwendung
immunohistochemistry
western blot
western blot
Proteins
Produktnummer
Beschreibung
Spezies
STAT6, GST tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Spezies
human