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Merck

UNG

uracil-DNA glycosylase

Synonyme:
DGU, HIGM4, HIGM5, UDG, UNG1, UNG15, UNG2
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(7374) Summary: This gene encodes one of several uracil-DNA glycosylases. One important function of uracil-DNA glycosylases is to prevent mutagenesis by eliminating uracil from DNA molecules by cleaving the N-glycosylic bond and initiating the base-excision repair (BER) pathway. Uracil bases occur from cytosine deamination or misincorporation of dUMP residues. Alternative promoter usage and splicing of this gene leads to two different isoforms: the mitochondrial UNG1 and the nuclear UNG2. The UNG2 term was used as a previous symbol for the CCNO gene (GeneID 10309), which has been confused with this gene, in the literature and some databases. [provided by RefSeq, Nov 2010]
  • Mouse(22256) uracil DNA glycosylase
  • Rat(304577) uracil-DNA glycosylase
  • Thale Cress(821394) uracil dna glycosylase
  • fruit fly(44538) uniungula
  • dog(486315) uracil-DNA glycosylase
  • chicken(374010) uracil-DNA glycosylase
  • cow(511381) uracil-DNA glycosylase
  • domestic cat(101094053) uracil-DNA glycosylase
  • sheep(101115316) uracil-DNA glycosylase
  • naked mole-rat(101717051) uracil-DNA glycosylase
  • domestic guinea pig(100730581) uracil-DNA glycosylase

Custom & Knockdown Gene Products

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-Uracil-DNA glycosylase Antibody, clone 8G10.1, clone 8G10.1, from mouse,
Speziesreaktivität
chimpanzee, human, monkey
Anwendung
immunohistochemistry
western blot
Anti-UNG1 Antibody, from rabbit, purified by affinity chromatography,
Speziesreaktivität
human, mouse
Anwendung
immunohistochemistry
western blot
Anti-Ung Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunofluorescence
Anti-UNG1 antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
Anwendung
immunofluorescence
immunohistochemistry

western blot
KD-Validated Anti Uracil DNA Glycosylase Antibody, clone 24GB2530, Rabbit Monoclonal, clone 24GB2530, recombinant rabbit monoclonal, expressed in HEK293 cells,
Speziesreaktivität
human
Anwendung
flow cytometry
immunofluorescence

western blot

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting human UNG,
Spezies
human