Merck
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D1411

Sigma-Aldrich

d-Desthiobiotin

≥98% (TLC)

Synonym(s):
5-Methyl-2-oxo-4-imidazolidinhexansäure
Empirical Formula (Hill Notation):
C10H18N2O3
CAS Number:
Molecular Weight:
214.26
EC-Nummer:
MDL-Nummer:
eCl@ss:
34058011
PubChem Substanz-ID:
NACRES:
NA.25

Qualitätsniveau

200

Assay

≥98% (TLC)

Form

powder

Lagertemp.

2-8°C

SMILES string

C[C@@H]1NC(=O)N[C@@H]1CCCCCC(O)=O

InChI

1S/C10H18N2O3/c1-7-8(12-10(15)11-7)5-3-2-4-6-9(13)14/h7-8H,2-6H2,1H3,(H,13,14)(H2,11,12,15)/t7-,8+/m0/s1

InChI key

AUTOLBMXDDTRRT-JGVFFNPUSA-N

Anwendung

d-Desthiobiotin wird in der Affinitätschromatografie und Proteinchromatografie verwendet. Es kann für Proteinmarkierung, -nachweis und -isolierung eingesetzt werden.
d-Desthiobiotin has been used as a component of elution buffers:
  • to elute the precipitated proteins from the resin during coimmunoprecipitation
  • to elute human Cdc45–MCM–GINS (CMG) helicase during chromatographic protein purification
  • to elute the heterodimeric kinesin family member 3A/B (KIF3A/B) and kinesin associated protein 3 (KAP3)-binding APC armadillo (APCARM) domain during chromatographic purification

Verpackung

500 mg in poly bottle
1 g in poly bottle

Biochem./physiol. Wirkung

Desthiobiotin is a non-sulfur containing biotin derivative that binds less strongly to biotin-binding proteins and is easily dislocated by biotin.

Sonstige Hinweise

Tandem-Massenspektrometriedaten, die unabhängig vom Scripps Center for Metabolomics generiert wurden, können eingesehen oder in pdf-Format heruntergeladen werden. D1411.pdf Die getesteten Metaboliten sind in der METLIN-Metabolitendatenbank des Scripps Center for Metabolomics aufgeführt. Weitere Informationen finden Sie auf sigma.com/metlin.

Lagerklassenschlüssel

13 - Non Combustible Solids

WGK

WGK 3

Flammpunkt F

Not applicable

Flammpunkt C

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)

Certificate of Analysis

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Certificate of Origin

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