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Sigma-Aldrich

(±)-6-Hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid

97%

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Synonym(s):
Trolox
Empirical Formula (Hill Notation):
C14H18O4
CAS Number:
Molecular Weight:
250.29
Beilstein:
1384051
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

97%

storage condition

under inert gas

mp

187-189 °C (lit.)

storage temp.

2-8°C

SMILES string

Cc1c(C)c2OC(C)(CCc2c(C)c1O)C(O)=O

InChI

1S/C14H18O4/c1-7-8(2)12-10(9(3)11(7)15)5-6-14(4,18-12)13(16)17/h15H,5-6H2,1-4H3,(H,16,17)

InChI key

GLEVLJDDWXEYCO-UHFFFAOYSA-N

Gene Information

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This Item
253847391913532576
2,3,4-Trihydroxybenzoic acid 97%

253847

2,3,4-Trihydroxybenzoic acid

Chromone-3-carboxylic acid 97%

532576

Chromone-3-carboxylic acid

Quality Level

200

Quality Level

100

Quality Level

100

Quality Level

100

storage temp.

2-8°C

storage temp.

-

storage temp.

-

storage temp.

-

mp

187-189 °C (lit.)

mp

~205 °C (dec.) (lit.)

mp

162 °C (dec.) (lit.)

mp

202-205 °C (lit.)

storage condition

under inert gas

storage condition

-

storage condition

-

storage condition

-

Gene Information

rat ... Akr1b1(24192)

Gene Information

-

Gene Information

-

Gene Information

human ... PTPN1(5770)

General description

(±)-6-Hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid (Trolox) exhibits radical scavenging and antioxidant activities.

Application

(±)-6-Hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid (Trolox) has been used in 6-hydroxy-2,5,7,8-tetramethyl chromane-2-carboxylic acid equivalent antioxidant assay (TEAC) to determine the total antioxidant capacity of different fruit species.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Legal Information

related product

Product No.
Description
Pricing

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Jessica Scalzo et al.
Nutrition (Burbank, Los Angeles County, Calif.), 21(2), 207-213 (2005-02-23)
We wanted to determine the total antioxidant capacity (6-hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid equivalent antioxidant assay; TEAC) of different species and cultivars (strawberry and apple) and to characterize the TEAC among fruits of the same varieties (peach and apricot) but grafted on different
Functional Analogues of the Dioxygen Reduction Site in Cytochrome Oxidase:? Mechanistic Aspects and Possible Effects of CuB
Boulatov R, et al.
Journal of the American Chemical Society, 124(40), 11923-11923 (2002)
Leonel N Leal et al.
Journal of the science of food and agriculture, 99(9), 4296-4303 (2019-03-01)
Due to the growing public concern regarding the addition of chemical antioxidants to foods, focus has shifted towards natural alternatives. Because of their antioxidant potential, culinary herbs and spices have long been used to extend the shelf-life of foods. However
Ming Yuan Heng et al.
Food chemistry, 221, 1388-1393 (2016-12-17)
In this study, extraction of immature fruits using an environmentally friendly pressurized hot water extraction (PHWE) method was compared with the traditional reflux method. Extracts were tested for their polyphenol content using the Folin-Ciocalteu assay and for their antioxidant activity
D A Kirke et al.
Food chemistry, 221, 1104-1112 (2016-12-17)
Due to their high anti-oxidant activity, phlorotannins represent potential natural alternatives to synthetic preservatives currently used within the food industry. However, their successful integration into food products requires research into their chemical integrity, particularly when selecting appropriate storage conditions. Subsequently

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