Merck
All Photos(3)

1.00013

SAFC

Acetone

EMPROVE® ESSENTIAL, Ph. Eur., BP, JPE, NF

Synonym(s):
Dimethyl ketone, Propanone, 2-Propanone
Linear Formula:
CH3COCH3
CAS Number:
Molecular Weight:
58.08
Beilstein:
635680
MDL number:
EC Index Number:
200-662-2

Agency

BP
JPE
NF
Ph. Eur.

Quality Level

vapor density

2 (vs air)

vapor pressure

184 mmHg ( 20 °C)

description

EMPROVE® ESSENTIAL Ph Eur,BP,JPE,NF

product line

EMPROVE® ESSENTIAL

assay

≥99% (GC)

form

liquid

autoignition temp.

465 °C (DIN 51794)

expl. lim.

13.2 %

technique(s)

API processing | polymorph screening: suitable

refractive index

n20/D 1.359 (lit.)

pH

5-6 (20 °C, 395 g/L in H2O)

capacity

1000  g/kg water absorbing capacity

bp

56 °C/760 mmHg (lit.)

mp

−94 °C (lit.)

transition temp

flash point <-20 °C

density

0.791 g/mL at 25 °C (lit.)

application(s)

biopharma process and formulation
liquid formulation
pharmaceutical

storage temp.

2-30°C

SMILES string

CC(C)=O

InChI

1S/C3H6O/c1-3(2)4/h1-2H3

InChI key

CSCPPACGZOOCGX-UHFFFAOYSA-N

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General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Acetone is used as solvent in a variety of pharmaceutical production processes, e. g. tablet coating, granulation, and microsphere production. It is also applied as solvent or co-solvent in topical formulations.
Acetone′s luminesence intensity is dependent upon the solution components . The absorption of UV light by acetone, results in its photolysis and the production of radials .

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

FlameExclamation mark

Signal Word

Danger

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3

Target Organs

Central nervous system

Supplementary Hazards

Storage Class Code

3 - Flammable liquids

WGK

WGK 1

Flash Point(F)

1.4 °F - closed cup

Flash Point(C)

-17.0 °C - closed cup

Certificate of Analysis

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Certificate of Quality

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What is the Emprove® Program?

The Emprove® Program is a system providing comprehensive and thorough documentation of our filters and single-use components, pharma raw materials, and starting materials.

Material Qualification Dossier

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Quality Management Dossier

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Operational Excellence Dossier

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Why are these documents unavailable?
Emprove® Dossiers contain information intended to support the registration process and risk assessment activities of pharmaceutical producers and contain confidential information. Please contact us if you would like access.

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