Merck
All Photos(2)

1.06441

SAFC

Sodium fluoride

EMPROVE® API Ph Eur,BP,USP

Synonym(s):
Sodium fluoride
Empirical Formula (Hill Notation):
FNa
CAS Number:
Molecular Weight:
41.99
MDL number:
EC Index Number:
231-667-8

Quality Level

Agency

BP
Ph. Eur.
USP

vapor pressure

1 hPa ( 1077 °C)

product line

EMPROVE® API

form

crystals

potency

148.5 mg/kg LD50, oral (Rat)

pH

10.2 (20 °C, 40 g/L in H2O)

mp

996 °C

density

2.8 g/cm3 at 20 °C

application(s)

liquid formulation
pharmaceutical
semi-solid formulation
solid formulation

storage temp.

2-25°C

InChI

1S/FH.Na/h1H;/q;+1/p-1

InChI key

PUZPDOWCWNUUKD-UHFFFAOYSA-M

Related Categories

General description

We provide industry-leading production know-how and comprehensive regulatory support for high-quality APIs, backed by nearly 200 years of experience. From a complete portfolio of innovative folates to custom synthesis, our customized and scalable solutions meet your specific production needs. As part of our EMPROVE® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Sodium fluoride is used in mouth hygiene, as a trace element for fluoride source in clinical nutrition and in dietary supplements. Sodium fluoride Emprove® API is manufactured according to ICH Q7 guidelines. A CEP and US-DMF are available.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Skull and crossbones

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2

Supplementary Hazards

Storage Class Code

6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

What is the Emprove® Program?

The Emprove® Program is a system providing comprehensive and thorough documentation of our filters and single-use components, pharma raw materials, and starting materials.

Elemental Impurities Information

Available by subscription or for a fee

API Information Package

Available by subscription or for a fee

Learn more about the benefits an Emprove® Program subscription can provide
Why are these documents unavailable?
Emprove® Dossiers contain information intended to support the registration process and risk assessment activities of pharmaceutical producers and contain confidential information. Please contact us if you would like access.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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