Merck

1.37028

SAFC

Glycerol

greener alternative

anhydrous (vegetable), EMPROVE® EXPERT, Ph. Eur., BP, JP, USP, ACS

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Synonym(s):
1,2,3-Propanetriol, Trihydroxylpropane, Protol, Glycerin, 1,2,3-Propanetriol, Glycerin
Linear Formula:
HOCH2CH(OH)CH2OH
CAS Number:
Molecular Weight:
92.09
Beilstein:
635685
MDL number:
EC Index Number:
200-289-5

grade

ACS reagent

Quality Level

Agency

BP
JP
Ph. Eur.
USP

vapor density

3.1 (vs air)

vapor pressure

<1 mmHg ( 20 °C)

product line

EMPROVE® EXPERT

Assay

≤98.0-101.0% (calculated on anhydrous substance, alkalimetric)
≥99.5% (calculated on anhydrous substance, GC)

form

liquid

autoignition temp.

698 °F

expl. lim.

2.6-11.3 % (v/v)

greener alternative product characteristics

Safer Solvents and Auxiliaries
Use of Renewable Feedstocks
Learn more about the Principles of Green Chemistry.

technique(s)

electrophoresis: suitable

refractive index

n20/D 1.474 (lit.)

pH

5 (20 °C, 100 g/L in H2O)

bp

182 °C/20 mmHg (lit.)

mp

20 °C (lit.)

transition temp

flash point 199 °C

density

1.25 g/mL (lit.)

application(s)

liquid formulation
ophthalmics
parenterals
pharma/biopharma processes
pharmaceutical

greener alternative category

storage temp.

2-30°C

SMILES string

OCC(O)CO

InChI

1S/C3H8O3/c4-1-3(6)2-5/h3-6H,1-2H2

InChI key

PEDCQBHIVMGVHV-UHFFFAOYSA-N

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This Item
911046G6279G9012
Glycerol anhydrous (vegetable), EMPROVE&#174; EXPERT, Ph. Eur., BP, JP, USP, ACS

SAFC

1.37028

Glycerol

-
Glycerol BioRenewable, &#8805;99.5%

Sigma-Aldrich

911046

Glycerol

-
Glycerol BioXtra, &#8805;99% (GC)

Sigma-Aldrich

G6279

Glycerol

Premium Grade
Glycerol &#8805;99.5%

Sigma-Aldrich

G9012

Glycerol

-
vapor density

3.1 (vs air)

vapor density

3.1 (vs air)

vapor density

3.1 (vs air)

vapor density

3.1 (vs air)

vapor pressure

<1 mmHg ( 20 °C)

vapor pressure

<1 mmHg ( 20 °C)

vapor pressure

<1 mmHg ( 20 °C)

vapor pressure

<1 mmHg ( 20 °C)

assay

≤98.0-101.0% (calculated on anhydrous substance, alkalimetric), ≥99.5% (calculated on anhydrous substance, GC)

assay

≥99.5%

assay

≥99% (GC)

assay

≥99.5%

form

liquid

form

liquid

form

viscous liquid

form

viscous liquid

autoignition temp.

698 °F

autoignition temp.

698 °F

autoignition temp.

698 °F

autoignition temp.

698 °F

General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.
We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Green Chemistry. This product is a bio-based glycerol and is aligned with the 5th principle of Green Chemistry "Safer Solvents and Auxiliaries" and 7th principle "Use of Renewable Feedstock". Click here for more details.

Application

Glycerol can be used in a wide variety of solid, semi-solid and liquid formulations, including ophthalmic, oral solid and oral liquid dosages, tablet coatings, creams and gels. It is applied for its humectant, emollient, solvent/cosolvent, viscosity increasing, and plasticizer properties.
Glycerol anhydrous (vegetable) Emprove® Expert is low in endotoxins and bioburden, making it the right choice for your high-risk applications.
Glycerol is used both in sample preparation and gel formation for polyacrylamide gel electrophoresis. Glycerol (5-10%) increases the density of a sample so that the sample will layer at the bottom of a gel′s sample well. Glycerol is also used to aid in casting gradient gels and as a protein stabilizer and storage buffer component.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

390.2 °F - Pensky-Martens closed cup

Flash Point(C)

199 °C - Pensky-Martens closed cup


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705578-5MG-PW

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