247588

Salicylic acid

ACS reagent, ≥99.0%

• Synonym(s): 2-Hydroxybenzoic acid
• Linear Formula: 2^-(HO)C₆H₄CO₂H
• CAS Number: 69-72-7
• Molecular Weight: 138.12
• Beilstein: 774890
• EC Number: 200-712-3
• MDL number: MFCD00002439
• PubChem Substance ID: 24854876

Properties

• grade: ACS reagent
• Quality Level: 200
• vapor density: 4.8 (vs air)
• vapor pressure: 1 mmHg ( 114 °C)
• assay: ≥99.0%
• impurities: H₂SO₄, passes test (darkened)
• ign. residue: ≤0.01%
• bp: 211 °C (lit.)
• mp: 158-161 °C (lit.)
• anion traces: chloride (Cl^-): ≤0.001%; sulfate (SO₄^2-): ≤0.003%
• cation traces: Fe: ≤2 ppm; heavy metals (as Pb): ≤5 ppm
• SMILES string: OC(=O)c1ccccc1O
• InChI: 1S/C7H6O3/c8-6-4-2-1-3-5(6)7(9)10/h1-4,8H,(H,9,10)
• InChI key: YGSDEFSMJLZEOE-UHFFFAOYSA-N
• Gene Information: human ... ALB(213) , PTPN1(5770)

Description

General description

Salicylic acid is mainly used as the precursor to synthesize aspirin, a commonly used analgesic and antipyretic. Due to its keratolytic action, it is also used in topical ointments.

Application

Salicylic acid has been used:

• to study its antimicrobial effect in vitro and in situ against Penicillium expansum
• as one of the chemical compound in exposure-based validation of in vitro gastrulation model employed in developmental toxicity screening assays
• as a reference standard in salicylate quantification by reverse-phase high-performance liquid chromatography (RP-HPLC)

Packaging

2.5, 100, 500 g in poly bottle

Biochem/physiol Actions

Salicylic acid (SA) delivers local and systemic acquired resistance (LAR and SAR) against various diseases in plants. It acts as a secondary metabolite and regulate various physiological processes such as, seed germination, seedling establishment, cell growth, respiration, stomatal closure and senescence-associated gene expression. In addition, SA also controls abiotic stress, basal thermotolerance, nodulation in legumes and fruit yield. It plays a vital role in modulation of flowering and thermogenesis (heat production) in plants. SA together with reactive oxygen species (ROS) and nitric oxide (NO) triggers cell death in plants.

Safety Information

• Pictograms: GHS05,GHS07,GHS08
• Signal Word: Danger
• Hazard Statements: H302 - H318 - H361d
• Precautionary Statements: P202 - P264 - P280 - P301 + P312 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Eye Dam. 1 - Repr. 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): 314.6 °F - closed cup
• Flash Point(C): 157 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves