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27301

Sigma-Aldrich

Salicylic acid

meets analytical specification of Ph. Eur., BP, USP, 99.5-100.5% (calc. to the dried substance)

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Synonym(s):
2-Hydroxybenzoic acid
Linear Formula:
2-(HO)C6H4CO2H
CAS Number:
Molecular Weight:
138.12
Beilstein:
774890
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.21

vapor density

4.8 (vs air)

Quality Level

vapor pressure

1 mmHg ( 114 °C)

Assay

99.5-100.5% (calc. to the dried substance)

quality

meets analytical specification of Ph. Eur., BP, USP

impurities

residual solvents, complies
≤0.001% heavy metals (as Pb)
≤0.2% related subst. (HPLC)

ign. residue

≤0.05% (as SO4)

loss

≤0.3% loss on drying

bp

211 °C (lit.)

mp

158-161 °C (lit.)
158-161 °C

anion traces

chloride (Cl-): ≤50 mg/kg
sulfate (SO42-): ≤200 mg/kg

suitability

complies for appearance of solution
complies for identity

application(s)

pharmaceutical (small molecule)

SMILES string

OC(=O)c1ccccc1O

InChI

1S/C7H6O3/c8-6-4-2-1-3-5(6)7(9)10/h1-4,8H,(H,9,10)

InChI key

YGSDEFSMJLZEOE-UHFFFAOYSA-N

Gene Information

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This Item
S5922247588S7401
Salicylic acid meets analytical specification of Ph. Eur., BP, USP, 99.5-100.5% (calc. to the dried substance)

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27301

Salicylic acid

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Salicylic acid

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Salicylic acid

vapor pressure

1 mmHg ( 114 °C)

vapor pressure

1 mmHg ( 114 °C)

vapor pressure

1 mmHg ( 114 °C)

vapor pressure

1 mmHg ( 114 °C)

assay

99.5-100.5% (calc. to the dried substance)

assay

≥99.0%

assay

≥99.0%

assay

≥99% (HPLC)

impurities

residual solvents, complies, ≤0.001% heavy metals (as Pb), ≤0.2% related subst. (HPLC)

impurities

≤0.015% Phosphorus (P), ≤0.1% Insoluble matter

impurities

H2SO4, passes test (darkened)

impurities

-

bp

211 °C (lit.)

bp

211 °C (lit.)

bp

211 °C (lit.)

bp

211 °C (lit.)

mp

158-161 °C (lit.)

mp

158-161 °C (lit.)

mp

158-161 °C (lit.)

mp

158-161 °C (lit.)

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Repr. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

314.6 °F - closed cup

Flash Point(C)

157 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Rapid colorimetric determination of nitrate in plant tissue by nitration of salicylic acid1.
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Communications in Soil Science and Plant Analysis, 6(1), 71-80 (1975)
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British journal of clinical pharmacology, 38(4), 349-355 (1994-10-01)
1. Five rheumatoid patients with a knee joint effusion participated in the study. An aqueous solution (0.1 to 0.2 ml) containing paracetamol, salicylate, diclofenac and [125I]-albumin was injected into a given joint to yield target concentrations of approximately 20 micrograms
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Acetylsalicylic acid (Aspirin) is rapidly metabolized to salicylic acid (salicylate) and other compounds, including gentisic acid and salicyluric acid. Monitoring of salicylate and its metabolites is of toxicological, pharmacological and biomedical interest. Three capillary electrophoresis (CE) methods featuring alkaline aqueous

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