Merck
All Photos(1)

29221

Sigma-Aldrich

Ethanol

tested according to Ph. Eur.

Synonym(s):
Ethanolum (96 per centum), Ethyl alcohol
Linear Formula:
CH3CH2OH
CAS Number:
Molecular Weight:
46.07
Beilstein:
1718733
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.55

Quality Level

Agency

USP/NF
tested according to Ph. Eur.

vapor density

1.59 (vs air)

vapor pressure

44.6 mmHg ( 20 °C)

form

liquid

autoignition temp.

683 °F

expl. lim.

19 %, 60 °F

refractive index

n20/D 1.3600 (lit.)

bp

78 °C (lit.)

mp

−114 °C (lit.)

solubility

H2O: soluble

density

0.789 g/mL at 25 °C (lit.)

application(s)

pharmaceutical (small molecule)

SMILES string

CCO

InChI

1S/C2H6O/c1-2-3/h3H,2H2,1H3

InChI key

LFQSCWFLJHTTHZ-UHFFFAOYSA-N

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Application

Ethanol has been used in indirect immunofluorescence for washing the mouse tissues section and then mounted in elvanol for visualizing with a BX60 photomicroscope. It has also been used for thymocyte preparation.

Biochem/physiol Actions

Ethanol provides controlled pH, temperature and ionic strength for protein separation. It blocks the ion current induced by the glutamate receptor agonist N-methyl-D-aspartate (NMDA) in hippocampal neurons.

Footnote

1Distribution and use of ethyl alcohol in Switzerland require a license from the Swiss Federal Alcohol Administration

Pictograms

FlameExclamation mark

Signal Word

Danger

Hazard Statements

Precautionary Statements

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 2

Storage Class Code

3 - Flammable liquids

WGK

WGK 1

Flash Point(F)

55.4 °F

Flash Point(C)

13 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

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Certificate of Origin

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M G Mahoney et al.
The Journal of clinical investigation, 103(4), 461-468 (1999-02-18)
Patients with pemphigus foliaceus (PF) have blisters on skin, but not mucous membranes, whereas patients with pemphigus vulgaris (PV) develop blisters on mucous membranes and/or skin. PF and PV blisters are due to loss of keratinocyte cell-cell adhesion in the
Y Gavrieli et al.
The Journal of cell biology, 119(3), 493-501 (1992-11-01)
Programmed cell death (PCD) plays a key role in developmental biology and in maintenance of the steady state in continuously renewing tissues. Currently, its existence is inferred mainly from gel electrophoresis of a pooled DNA extract as PCD was shown
D M Lovinger et al.
Science (New York, N.Y.), 243(4899), 1721-1724 (1989-03-31)
The ion current induced by the glutamate receptor agonist N-methyl-D-aspartate (NMDA) in voltage-clamped hippocampal neurons was inhibited by ethanol (EtOH). Inhibition increased in a concentration-dependent manner over the range 5 to 50 mM, a range that also produces intoxication. The
Cem Kuscu et al.
Nature biotechnology, 32(7), 677-683 (2014-05-20)
RNA-guided genome editing with the CRISPR-Cas9 system has great potential for basic and clinical research, but the determinants of targeting specificity and the extent of off-target cleavage remain insufficiently understood. Using chromatin immunoprecipitation and high-throughput sequencing (ChIP-seq), we mapped genome-wide
S Enocksson et al.
The Journal of clinical investigation, 95(5), 2239-2245 (1995-05-01)
Although it is well established in several mammalian species that beta 3-adrenoceptors play a major role in regulating lipolysis and thermogenesis in adipose tissue, the functional existence and role of this receptor subtype in man has been controversial. We investigated

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