L4509

Sodium dodecyl sulfate

ReagentPlus^®, ≥98.5% (GC)

• Synonym(s): Dodecyl sodium sulfate, Dodecyl sulfate sodium salt, Lauryl sulfate sodium salt, SDS, Sodium lauryl sulfate
• Linear Formula: CH₃(CH₂)₁₁OSO₃Na
• CAS Number: 151-21-3
• Molecular Weight: 288.38
• Beilstein: 3599286
• EC Number: 205-788-1
• MDL number: MFCD00036175
• eCl@ss: 39093306
• PubChem Substance ID: 24896370
• NACRES: NA.21

Properties

• description: anionic
• Quality Level: 200
• product line: ReagentPlus^®
• Assay: ≥98.5% (GC)
• mol wt: micellar avg mol wt 18,000
• aggregation number: 62
• CMC: 7-10 mM (20-25°C)
• mp: 204-207 °C (lit.)
• transition temp: cloud point >100 °C
• solubility: water: soluble
• HLB: 40
• SMILES string: [Na+].CCCCCCCCCCCCOS([O-])(=O)=O
• InChI: 1S/C12H26O4S.Na/c1-2-3-4-5-6-7-8-9-10-11-12-16-17(13,14)15;/h2-12H2,1H3,(H,13,14,15);/q;+1/p-1
• InChI key: DBMJMQXJHONAFJ-UHFFFAOYSA-M

Description

General description

Sodium dodecyl sulphate (SDS) is an anionic surfactant. It is also called as lauryl sulphate.

Application

Sodium dodecyl sulphate (SDS) has been used:

• in the characterization of Enterobacteriaceae strain based on sensitivity to selective compounds
• to treat human skin in vitro and in vivo to evaluate the role of nuclear localization of 27-kDa heat shock protein (HSP27) in potential skin irritation
• in the decellularization of porcine heart valve tissue
• to treat sperm for in vitro induction of sperm decondensation

Anionic detergent

Biochem/physiol Actions

Sodium dodecyl sulphate (SDS) helps to quickly disrupt the biological membranes. It is usually used as one of the major constituent of several reagents, that are used to purify nucleic acids. SDS can block the activity of RNase and deoxyribonuclease (DNase).

Legal Information

ReagentPlus is a registered trademark of Sigma-Aldrich Co. LLC

Safety Information

• Pictograms: GHS02,GHS05,GHS07
• Signal Word: Danger
• Hazard Statements: H228 - H302 + H332 - H315 - H318 - H335 - H412
• Precautionary Statements: P210 - P273 - P280 - P301 + P312 - P304 + P340 + P312 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Flam. Sol. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 4.1B - Flammable solid hazardous materials
• WGK: WGK 2
• Flash Point(F): 338.0 °F
• Flash Point(C): 170 °C
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves