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M0200000

Mannitol

European Pharmacopoeia (EP) Reference Standard

Synonym(s):
D-Mannitol, Mannite
Empirical Formula (Hill Notation):
C6H14O6
CAS Number:
Molecular Weight:
182.17
Beilstein:
1721898
MDL number:
PubChem Substance ID:
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

mannitol

manufacturer/tradename

EDQM

mp

167-170 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO

InChI

1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4-,5-,6-/m1/s1

InChI key

FBPFZTCFMRRESA-KVTDHHQDSA-N

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This Item
BP10071.004941375105
Mannitol European Pharmacopoeia (EP) Reference Standard

M0200000

Mannitol

Mannitol British Pharmacopoeia (BP) Reference Standard

BP1007

Mannitol

Parteck® M 100 (Mannitol) EMPROVE® ESSENTIAL, Ph. Eur., BP, ChP, JP, USP, E 421

SAFC

1.00494

Parteck® M 100 (Mannitol)

Mannitol United States Pharmacopeia (USP) Reference Standard

USP

1375105

Mannitol

manufacturer/tradename

EDQM

manufacturer/tradename

BP

manufacturer/tradename

-

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

application(s)

-

application(s)

liquid formulation
pharmaceutical
solid formulation

application(s)

pharmaceutical (small molecule)

format

neat

format

neat

format

-

format

neat

API family

mannitol

API family

mannitol

API family

-

API family

mannitol

mp

167-170 °C (lit.)

mp

167-170 °C (lit.)

mp

164-169 °C

mp

167-170 °C (lit.)

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets, has been developed and issued under the Authority of the Issuing Pharmacopoeia.

For further information and support please go to the website of the issuing Pharmacopoeia.

Application

This European Pharmacopoeia reference standard is intended for use only as specifically prescribed in the European Pharmacopoeia. Their suitability for any other use is not guaranteed and is the sole responsibility of the user. This standard is not intended for human or animal use.
Established for the preparation of the below-given solutions as per European Pharmacopoeia:

  • Reference solution (b) in the testing of related substances using liquid chromatography (General text 2.2.29) in isomalt, according to the monograph 1531
  • Reference solutions (a) in the identification of mannitol using thin-layer chromatography (General text 2.2.27) and infra-red spectroscopy and testing of related substances and assay using liquid chromatography (General text 2.2.29), according to the monograph 0559
  • Reference solution (b) in the identification of sorbitol using thin-layer chromatography (General text 2.2.27), according to the monograph 0435
  • Reference solution (b) in the testing of related substances using gas chromatography (General text 2.2.28), according to the monograph 1381

Biochem/physiol Actions

A sugar alcohol sweet tastant. Used in sweetness inhibition studies.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1


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Heikki O Koskela et al.
Chest, 125(6), 1985-1992 (2004-06-11)
To define whether coughing during mannitol challenge is a nonspecific side effect of this challenge or is associated with asthma. A prospective study. University hospital. Thirty-seven steroid-naive, asthmatic subjects and 10 healthy subjects. The participants completed a symptom questionnaire, recorded

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