PHR1168

Ofloxacin

Pharmaceutical Secondary Standard; Certified Reference Material

• Empirical Formula (Hill Notation): C₁₈H₂₀FN₃O₄
• CAS Number: 82419-36-1
• Molecular Weight: 361.37
• UNSPSC Code: 41116107
• PubChem Substance ID: 329823185
• NACRES: NA.24
• MDL number: MFCD00226105

Properties

• Product Name: Ofloxacin, Pharmaceutical Secondary Standard; Certified Reference Material
• SMILES string: Fc1cc2c3[n](cc([c]2=O)C(=O)O)C(COc3c1N4CCN(CC4)C)C
• InChI: 1S/C18H20FN3O4/c1-10-9-26-17-14-11(16(23)12(18(24)25)8-22(10)14)7-13(19)15(17)21-5-3-20(2)4-6-21/h7-8,10H,3-6,9H2,1-2H3,(H,24,25)
• InChI key: GSDSWSVVBLHKDQ-UHFFFAOYSA-N
• grade: certified reference material; pharmaceutical secondary standard
• agency: traceable to USP 1478108
• API family: ofloxacin, ofloxacin
• CofA: current certificate can be downloaded
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• application(s): pharmaceutical (small molecule)
• format: neat
• storage temp.: 2-30°C
• Quality Level: 300

Description

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

To see an example of a Certificate of Analysis for this material enter LRAA7180 in the slot below. This is an example certificate only and may not be the lot that you receive.

Values of analytes vary lot to lot.

Analysis Note

These secondary standards offer multi-traceability to the USP and EP (PhEur) primary standards, where they are available.

Application

Ofloxacin may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations[1][2] and serum samples[3] by chromatography[1] and spectrophotometry[1][2][3] techniques.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Ofloxacin is an orally administered antimicrobial drug that is classified under the group of fluoroquinolones. It has high potency and shows a broad-spectrum antibacterial performance, as well as short selection of resistant bacteria.[4]

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable