PHR1219

Acetone

Pharmaceutical Secondary Standard; Certified Reference Material

• Linear Formula: CH₃COCH₃
• CAS Number: 67-64-1
• Molecular Weight: 58.08
• Beilstein: 635680
• EC Number: 200-662-2
• MDL number: MFCD00008765
• PubChem Substance ID: 329823226
• NACRES: NA.24

Properties

• Quality Level: 300
• grade: certified reference material; pharmaceutical secondary standard
• Agency: traceable to USP 1006801
• vapor density: 2 (vs air)
• vapor pressure: 184 mmHg ( 20 °C)
• CofA: current certificate can be downloaded
• expl. lim.: 13.2 %
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• refractive index: n20/D 1.359 (lit.)
• bp: 56 °C/760 mmHg (lit.)
• mp: −94 °C (lit.)
• density: 0.791 g/mL at 25 °C (lit.)
• application(s): pharmaceutical (small molecule)
• format: neat
• storage temp.: 2-30°C
• SMILES string: CC(C)=O
• InChI: 1S/C3H6O/c1-3(2)4/h1-2H3
• InChI key: CSCPPACGZOOCGX-UHFFFAOYSA-N

Description

General description

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Acetone is an organic compound and in contrast to petroleum based hexane, it is a biorenewable solvent obtained via fermentation. It is generally used as a solvent for many gums, resins, and in the production of plastics.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Acetone′s luminesence intensity is dependent upon the solution components . The absorption of UV light by acetone, results in its photolysis and the production of radials .

Analysis Note

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAB5525 in the slot below. This is an example certificate only and may not be the lot that you receive.

Safety Information

• Pictograms: GHS02,GHS07
• Signal Word: Danger
• Hazard Statements: H225 - H319 - H336
• Precautionary Statements: P210 - P233 - P240 - P241 - P242 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3
• Target Organs: Central nervous system
• Supplementary Hazards: EUH066
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 1
• Flash Point(F): 1.4 °F - closed cup
• Flash Point(C): -17.0 °C - closed cup