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Residual Solvent - Toluene

Pharmaceutical Secondary Standard; Certified Reference Material

Linear Formula:
CAS Number:
Molecular Weight:
EC Number:
MDL number:
PubChem Substance ID:

Quality Level


certified reference material
pharmaceutical secondary standard


traceable to USP 1601805

vapor density

3.2 (vs air)

vapor pressure

22 mmHg ( 20 °C)
26 mmHg ( 25 °C)


current certificate can be downloaded

autoignition temp.

997 °F

expl. lim.

7 %


HPLC: suitable
gas chromatography (GC): suitable

refractive index

n/D 1.496 (lit.)


110-111 °C (lit.)


-93 °C (lit.)


0.865 g/mL at 25 °C (lit.)


pharmaceutical (small molecule)


single component solution

storage temp.


SMILES string




InChI key


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General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Residual Solvent – Toluene is a certified reference material for the screening and quantification of residual solvents. This CRM is a secondary pharmaceutical reference standard and is traceable and qualified against the corresponding pharmacopeial standards.


These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.


To see an example of a Certificate of Analysis for this material enter LRAC1709 in the slot below. This is an example certificate only and may not be the lot that you receive.

Signal Word


Hazard Classifications

Aquatic Chronic 3 - Asp. Tox. 1 - Flam. Liq. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 2 - STOT SE 3

Target Organs

Central nervous system

Storage Class Code

3 - Flammable liquids



Flash Point(F)

39.2 °F

Flash Point(C)

4.0 °C

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

Enter Lot Number to search for Certificate of Origin (COO).

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Journal of neuropathology and experimental neurology, 63(1), 1-12 (2004-01-30)
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