S9251

Sulfanilamide

≥98%

• Synonym(s): 4-aminobenzenesulfonamide, p-Aminobenzenesulfonamide
• Linear Formula: H₂NC₆H₄SO₂NH₂
• CAS Number: 63-74-1
• Molecular Weight: 172.20
• Beilstein: 511852
• EC Number: 200-563-4
• MDL number: MFCD00007939
• eCl@ss: 39093202
• PubChem Substance ID: 24899829
• NACRES: NA.76

Properties

• Quality Level: 200
• Assay: ≥98%
• form: powder or crystals
• color: white to off-white
• mp: 164-166 °C (lit.)
• antibiotic activity spectrum: Gram-negative bacteria; Gram-positive bacteria
• Mode of action: DNA synthesis | interferes; enzyme | inhibits
• SMILES string: Nc1ccc(cc1)S(N)(=O)=O
• InChI: 1S/C6H8N2O2S/c7-5-1-3-6(4-2-5)11(8,9)10/h1-4H,7H2,(H2,8,9,10)
• InChI key: FDDDEECHVMSUSB-UHFFFAOYSA-N
• Gene Information: human ... CA1(759) , CA2(760) , CA5A(763) , CA5B(11238) , CA9(768) ; mouse ... Car13(71934) , Car5a(12352)

Description

General description

Chemical structure: sulfonamide

Biochem/physiol Actions

Sulfonamide antibiotic that blocks the synthesis of dihydrofolic acid by inhibiting the enzyme dihydropteroate synthase.
Mode of Action: A competitive inhibitor of dihydropteroate synthestase to block the synthesis of folic acid.
Anti-microbial Spectrum: Gram positive, Gram negative, Chlamydia
Mode of Resistance: Alteration of dihydropteroate synthase or alternative pathway for folic acid synthesis.

Other Notes

Keep container tightly closed in a dry and well-ventilated place.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves