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T8625

Sigma-Aldrich

L-Threonine

reagent grade, ≥98% (HPLC)

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Synonym(s):
(2S,3R)-2-Amino-3-hydroxybutyric acid
Linear Formula:
CH3CH(OH)CH(NH2)CO2H
CAS Number:
Molecular Weight:
119.12
Beilstein:
1721646
EC Number:
MDL number:
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.26

grade

reagent grade

Quality Level

Assay

≥98% (HPLC)

form

powder

color

white to off-white

mp

256 °C (dec.) (lit.)

solubility

H2O: 50 mg/mL, clear, colorless

application(s)

cell analysis

SMILES string

C[C@@H](O)[C@H](N)C(O)=O

InChI

1S/C4H9NO3/c1-2(6)3(5)4(7)8/h2-3,6H,5H2,1H3,(H,7,8)/t2-,3+/m1/s1

InChI key

AYFVYJQAPQTCCC-GBXIJSLDSA-N

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1 of 4

This Item
T8441T837589179
vibrant-m

T8625

L-Threonine

Essential Grade
vibrant-m

T8441

L-Threonine

Premium Grade
vibrant-m

T8375

DL-Threonine

-
vibrant-m

89179

L-Threonine

Premium Grade
form

powder

form

powder

form

powder

form

powder or crystals

assay

≥98% (HPLC)

assay

99.0-101.0%

assay

≥95% (titration)

assay

≥99.5% (NT)

mp

256 °C (dec.) (lit.)

mp

256 °C (dec.) (lit.)

mp

244 °C (dec.) (lit.)

mp

256 °C (dec.) (lit.)

solubility

H2O: 50 mg/mL, clear, colorless

solubility

H2O: 1 g/10 mL, clear, colorless

solubility

-

solubility

H2O: 50 mg/mL, clear, colorless

Quality Level

200

Quality Level

300

Quality Level

200

Quality Level

100

Application

L-threonine has been used for the selection of transformed cells. It has also been used to study the effects of amino acids in promoting food consumption in Drosophila melanogaster.

Biochem/physiol Actions

L-Threonine is an essential amino acid. It is involved in the synthesis of mucin, a protein supporting intestinal function and integrity. L-threonine has a role in the immune system, in O-linked glycosylation, protein phosphorylation and glycine synthesis.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Markerless Gene Editing in the Hyperthermophilic Archaeon Thermococcus kodakarensis
Alexandra M. Gehring
Bio-protocol, 7(22), 1-26 (2017)
An internal sensor detects dietary amino acids and promotes food consumption in Drosophila
Zhe Yang
Nature, 1-36 (2017)
Tamara Seredenina et al.
Antioxidants & redox signaling, 23(5), 490-513 (2014-02-04)
Voltage-gated proton channels are increasingly implicated in cellular proton homeostasis. Proton currents were originally identified in snail neurons less than 40 years ago, and subsequently shown to play an important auxiliary role in the functioning of reactive oxygen species (ROS)-generating
Mario Ost et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 29(4), 1314-1328 (2014-12-11)
Recent studies on mouse and human skeletal muscle (SM) demonstrated the important link between mitochondrial function and the cellular metabolic adaptation. To identify key compensatory molecular mechanisms in response to chronic mitochondrial distress, we analyzed mice with ectopic SM respiratory
Anne-Sophie Van Rompuy et al.
Journal of neuropathology and experimental neurology, 73(2), 159-174 (2014-01-16)
Mutations in the parkin gene are the most common cause of early-onset autosomal recessive Parkinson disease (PD). The pathogenic mechanisms of how parkin mutations lead to the development of PD are not fully understood. Studies of cell cultures and of

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