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27487

Sigma-Aldrich

Citric acid

BioUltra, anhydrous, ≥99.5% (T)

Linear Formula:
HOC(COOH)(CH2COOH)2
CAS Number:
Molecular Weight:
192.12
Beilstein:
782061
EC Number:
MDL number:
eCl@ss:
39021801
PubChem Substance ID:
NACRES:
NA.25

Quality Level

product line

BioUltra

assay

≥99.5% (T)

form

powder or crystals

expl. lim.

8 %, 65 °F

technique(s)

cell culture | hybridoma: suitable

impurities

insoluble matter, passes filter test

ign. residue

≤0.05% (as SO4)

loss

≤0.5% loss on drying, 110 °C

pH

1.0-2.0 (25 °C, 1 M in H2O)

pKa 

(1) 3.13, (2) 4.76, (3) 6.4

mp

153-159 °C (lit.)

solubility

H2O: 1 M at 20 °C, clear, colorless

anion traces

chloride (Cl-): ≤5 mg/kg
oxalate (C2O42-): ≤500 mg/kg
phosphate (PO43-): ≤5 mg/kg
sulfate (SO42-): ≤20 mg/kg
tartrate (C4H4O62-): ≤2000 mg/kg

cation traces

Al: ≤5 mg/kg
As: ≤0.1 mg/kg
Ba: ≤5 mg/kg
Bi: ≤5 mg/kg
Ca: ≤10 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤50 mg/kg
Li: ≤5 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Mo: ≤5 mg/kg
Na: ≤50 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Sr: ≤5 mg/kg
Zn: ≤5 mg/kg

λmax

260 nm (Amax: ≤0.20)
280 nm (Amax: ≤0.10)

SMILES string

OC(=O)CC(O)(CC(O)=O)C(O)=O

λ

1 M in H2O

UV absorption

λ: 260 nm Amax: 0.20
λ: 280 nm Amax: 0.10

InChI

1S/C6H8O7/c7-3(8)1-6(13,5(11)12)2-4(9)10/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)

InChI key

KRKNYBCHXYNGOX-UHFFFAOYSA-N

Gene Information

human ... SRC(6714)

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General description

Citric acid is a buffer component for triple-column amino acid analysis. It is an optimal buffer for dissociation of radioiodinated antibodies from viable murine tumor cells.

Other Notes

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. 27487.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

Enter Lot Number to search for Certificate of Origin (COO).

More Documents

Quotes and Ordering

T N Ferraro et al.
Analytical biochemistry, 143(1), 82-94 (1984-11-15)
A highly resolving triple-column amino acid analyzer with fluorometric detection is described. The reliability of this technique was evaluated and it was used in a baseline investigation of amino acids and related compounds in human cerebrospinal fluid (CSF). The procedure
R Ehrlich et al.
Journal of immunological methods, 26(4), 345-353 (1979-01-01)
Several low pH buffers were used in order to dissociate radioiodinated antibodies from sensitized living tumor cells. Three buffers were further tested for their dissociation abilities under different conditions of time and temperature, and for their influence on the eluted
Konrad Hoetzenecker et al.
European heart journal, 36(11), 676-685 (2013-01-17)
Supernatants of serum-free cultured mononuclear cells (MNC) contain a mix of immunomodulating factors (secretome), which have been shown to attenuate detrimental inflammatory responses following myocardial ischaemia. Inflammatory dilated cardiomyopathy (iDCM) is a common cause of heart failure in young patients.
Tetsuji Sawada et al.
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association, 18(1), 119-128 (2014-02-04)
The G-Project committee was erected by the Japan Society for Gastroenterological Carcinogenesis with an aim of establishing a new classification scheme based on molecular biological characteristics that would supplement the conventional TNM classification to better predict outcome. In a literature
Maria José Garcia-Fernandez et al.
Biofouling, 29(3), 261-271 (2013-02-27)
Prevention and management of wound infections receive a lot of attention, since the presence of micro-organisms interferes with the wound-healing process. The aim of this work was to use cyclodextrins (CDs) to endow hydrogels and gauzes with the ability to

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