Merck
All Photos(3)

31392

Sigma-Aldrich

Dextran from Leuconostoc spp.

Mr 450,000-650,000

Linear Formula:
(C6H10O5)n
CAS Number:
EC Number:
MDL number:
NACRES:
NA.25

form

powder

Quality Level

mol wt

Mr 450,000-650,000

loss

≤7% loss on drying

absorption

≤0.05 at 375 nm in H2O at 10%

storage temp.

room temp

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General description

Dextran is an extracellular bacterial polymer of D-glucopyranose that majorly comprises α-(1→6) linkage in the main chain and a varying amount of α-(1→2), α-(1→3), α-(1→4) branched linkages.

Application

Dextran from Leuconostoc spp. has been used:
  • in the isolation of human neutrophils from blood samples
  • for blood sedimentation
  • in the resuspension of human umbilical vein cells (HUVECs) for 3D microfluidic cellular adhesion assay

Biochem/physiol Actions

Dextran is commercially used as a drug, specifically as a blood plasma volume expander. It acts as an adjuvant, emulsifier, carrier, and stabilizer in the food, pharmaceutical, and chemical industries. Sephadex is a cross-linked dextran that aids the separation and purification of protein. Dextran is used as a thickener for jam and ice cream in the food industry. It hinders the crystallization of sugar and augments moisture retention. This in turn maintains the flavor and appearance of several food items.

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

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Certificate of Origin

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